Description

1-(2,5-Dichlorophenyl)-1-Tosylmethyl Isocyanide is a specialized organic building block featuring a reactive isocyanide functional group, making it a valuable intermediate for the synthesis of complex heterocycles and pharmaceuticals. Its core value lies in enabling advanced medicinal chemistry research and the development of novel active pharmaceutical ingredients (APIs). This compound is primarily needed by research scientists and process chemists in the pharmaceutical, agrochemical, and advanced materials sectors for applications in drug discovery and fine chemical synthesis.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex drug candidates and active pharmaceutical ingredients (APIs).
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides.
• Heterocyclic Chemistry: Serves as a crucial reagent in the construction of nitrogen-containing heterocyclic scaffolds via multicomponent reactions (MCRs) like the Ugi reaction.
• Medicinal Chemistry: Enables structure-activity relationship (SAR) studies and the exploration of new chemical entities in drug discovery programs.
• Fine Chemical Synthesis: Employed in custom synthesis and the production of high-value, complex organic molecules.
• Material Science: Potential precursor for functionalized polymers or specialty materials with tailored properties.

Basic Information

Item	Details
Product Name	1-(2,5-Dichlorophenyl)-1-Tosylmethyl Isocyanide
CAS No.	1330184-87-6
Molecular Formula	C15H11Cl2NO2S
Molecular Weight	340.22 g/mol
Synonyms	1-(2,5-Dichlorophenyl)-1-[(4-methylphenyl)sulfonyl]methyl isocyanide; 1-Isocyano-1-(2,5-dichlorophenyl)-1-tosylmethane; 1-Tosyl-1-(2,5-dichlorophenyl)methyl isocyanide; 2,5-Dichloro-α-isocyano-α-toluenesulfonyltoluene; (2,5-Dichlorophenyl)(tosylmethyl) isocyanide; TosMIC derivative, 2,5-dichloro substituted; Isocyanomethyl 2,5-dichlorophenyl tosyl ketone analog
EINECS	Contact for details

Quality Control

Our 1-(2,5-Dichlorophenyl)-1-Tosylmethyl Isocyanide is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and development. We provide comprehensive analytical data, including HPLC purity, NMR, and mass spectrometry confirmation. Certificates of Analysis (COA) are available for every batch upon request, detailing all relevant specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.