Description

6-Bromo-8-(Morpholin-4-Yl)-1,2,3,4-Tetrahydro-1,5-Naphthyridine is a high-value, heterocyclic organic compound featuring a brominated naphthyridine core substituted with a morpholine moiety. This specific molecular architecture makes it a crucial advanced pharmaceutical intermediate (API) and a versatile building block in modern synthetic chemistry. It is primarily sought after by research institutions and chemical manufacturers engaged in the development of novel active pharmaceutical ingredients (APIs), particularly within therapeutic areas such as oncology and central nervous system (CNS) disorders.

Application

• Pharmaceutical Intermediate: Serves as a key synthetic precursor in the multi-step synthesis of complex drug candidates and novel chemical entities (NCEs).
• Medicinal Chemistry Research: Used extensively in structure-activity relationship (SAR) studies and lead optimization for discovering new therapeutic agents.
• Kinase Inhibitor Development: The naphthyridine scaffold is common in kinase inhibitors, making this brominated derivative valuable for developing targeted cancer therapies.
• Chemical Synthesis Building Block: The bromine atom offers a reactive site for further functionalization via cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig).
• Agrochemical Research: Potential application as an intermediate in the synthesis of novel crop protection agents and pesticides.
• Material Science Exploration: Can be investigated as a monomer or functional component in the creation of specialized organic electronic materials.

Basic Information

Product Name	6-Bromo-8-(Morpholin-4-Yl)-1,2,3,4-Tetrahydro-1,5-Naphthyridine
CAS No.	1329835-80-4
Molecular Formula	C₁₂H₁₆BrN₃O
Molecular Weight	298.18 g/mol
Synonyms	6-Bromo-8-morpholino-1,2,3,4-tetrahydro-1,5-naphthyridine; 1,2,3,4-Tetrahydro-6-bromo-8-(4-morpholinyl)-1,5-naphthyridine; 8-Morpholino-6-bromo-1,2,3,4-tetrahydro-1,5-naphthyridine; 6-Bromo-8-morpholino-1,5-naphthyridine (partial); 1329835-80-4; 6-Bromo-8-morpholin-4-yl-1,2,3,4-tetrahydro-1,5-naphthyridine
EINECS	Contact for details

Quality Control

Our 6-Bromo-8-(Morpholin-4-Yl)-1,2,3,4-Tetrahydro-1,5-Naphthyridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our commitment to quality supports your R&D and cGMP-compliant production needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The compound may be light-sensitive; prolonged exposure to light should be avoided. Keep the container sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.