Description

α,4-Di-o-Acetyl Vanillylmandelic Acid Ethyl Ester is a high-purity synthetic intermediate of significant interest in advanced organic synthesis. This compound is valued for its role as a key building block in the development of complex molecules, particularly in pharmaceutical research. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for synthesizing novel active compounds and reference standards.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of potential drug candidates, especially those targeting neurological or metabolic pathways.
• Reference Standard: Used as an analytical standard in quality control laboratories for method development and validation.
• Organic Synthesis Building Block: Employed in multi-step synthetic routes to construct complex molecular architectures due to its protected functional groups.
• Biochemical Research: Utilized in studies related to catecholamine metabolism and related biochemical pathways.
• Process Chemistry Development: Serves as a model compound for scaling up and optimizing synthetic processes in pilot plants.

Basic Information

Product Name	α,4-Di-o-Acetyl Vanillylmandelic Acid Ethyl Ester
CAS No.	1329795-85-8
Molecular Formula	C18H22O9
Molecular Weight	382.36 g/mol
Synonyms	Ethyl 2-(4-(Acetyloxy)-3-methoxyphenyl)-2-(acetyloxy)acetate; VMA Ethyl Ester Diacetate; 3-Methoxy-4-hydroxymandelic Acid Ethyl Ester Diacetate; Vanillylmandelic Acid Ethyl Ester Diacetate; α,4-Di-O-acetylvanillylmandelic acid ethyl ester; 2-[4-(Acetyloxy)-3-methoxyphenyl]-2-(acetyloxy)acetic Acid Ethyl Ester
EINECS	Contact for details

Quality Control

Our α,4-Di-o-Acetyl Vanillylmandelic Acid Ethyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) documenting all critical quality attributes are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This material is moisture-sensitive; keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.