Description

tert-Butyl(S)-(1-(4-Chloropyridin-2-Yl)But-3-En-1-Yl)Carbamate is a high-purity chiral building block of significant interest in advanced organic synthesis. This compound matters as a key intermediate for constructing complex molecules with defined stereochemistry, which is critical for developing active pharmaceutical ingredients (APIs) and other fine chemicals. It is primarily needed by research and development teams in the pharmaceutical, agrochemical, and specialty chemical industries for applications in medicinal chemistry and process development.

Application

• Pharmaceutical Intermediate: A crucial chiral synthon in the research and development of novel Active Pharmaceutical Ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and infectious diseases.
• Medicinal Chemistry Research: Used in parallel and combinatorial synthesis for constructing focused libraries to explore structure-activity relationships (SAR) and identify new lead compounds.
• Asymmetric Synthesis: Serves as a versatile building block in catalytic asymmetric transformations and multi-step syntheses requiring high enantiomeric purity.
• Agrochemical Development: Employed in the synthesis of advanced, chiral crop protection agents and herbicides.
• Process Chemistry & Scale-Up: Used in the development and optimization of scalable synthetic routes from laboratory to pilot plant scale.
• Custom Synthesis & Contract Manufacturing: A key starting material for custom synthesis organizations (CSOs) and CDMOs (Contract Development and Manufacturing Organizations) serving the global life sciences market.

Basic Information

Product Name	tert-Butyl(S)-(1-(4-Chloropyridin-2-Yl)But-3-En-1-Yl)Carbamate
CAS No.	1329171-69-8
Molecular Formula	C14H17ClN2O2
Molecular Weight	280.75 g/mol
Synonyms	(S)-tert-Butyl (1-(4-chloropyridin-2-yl)but-3-en-1-yl)carbamate; (S)-N-Boc-1-(4-chloro-2-pyridinyl)-3-buten-1-amine; BOC-(S)-1-(4-Chloro-2-pyridyl)-3-butenylamine; tert-Butyl (S)-(1-(4-chloro-2-pyridinyl)-3-buten-1-yl)carbamate; (S)-1-(4-Chloropyridin-2-yl)but-3-en-1-amine N-Boc derivative; (S)-N-(tert-Butoxycarbonyl)-1-(4-chloropyridin-2-yl)but-3-en-1-amine; 1329171-69-8; Boc-Protected 4-Chloro-2-Pyridinyl Butenyl Amine (S-isomer)
EINECS	Contact for details

Quality Control

Our production of tert-Butyl(S)-(1-(4-Chloropyridin-2-Yl)But-3-En-1-Yl)Carbamate adheres to stringent quality management systems. The product undergoes rigorous analytical testing, including chiral HPLC, to ensure high chemical and enantiomeric purity suitable for demanding synthetic applications. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with each batch and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.