Description

4-Oxo-4-[(4-Pyridin-4-Yl-1,3-Thiazol-2-Yl)Amino]Butanoic Acid is a high-purity, advanced pharmaceutical intermediate featuring a unique molecular scaffold combining pyridine and thiazole rings. This compound is valued for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring targeted molecular interactions. It is primarily sought by research institutions and pharmaceutical companies engaged in the development of new drugs, especially within oncology and anti-infective research pipelines.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the multi-step synthesis of complex drug candidates and novel chemical entities.
• Medicinal Chemistry Research: Used extensively in hit-to-lead optimization and structure-activity relationship (SAR) studies due to its versatile heterocyclic structure.
• Kinase Inhibitor Development: A valuable scaffold for designing and synthesizing potential kinase inhibitors, targeting various disease pathways.
• Bioconjugation & Probe Synthesis: The carboxylic acid functional group allows for conjugation to other molecules, useful in creating biochemical probes or antibody-drug conjugates (ADCs).
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations providing custom synthesis and process development services for the pharmaceutical industry.
• Academic Research: Utilized in university and institutional labs for fundamental studies in organic synthesis and bioorganic chemistry.

Basic Information

Product Name	4-Oxo-4-[(4-Pyridin-4-Yl-1,3-Thiazol-2-Yl)Amino]Butanoic Acid
CAS No.	1328814-77-2
Molecular Formula	C₁₂H₁₁N₃O₃S
Molecular Weight	277.30 g/mol
Synonyms	4-[(4-Pyridin-4-yl-1,3-thiazol-2-yl)amino]-4-oxobutanoic acid; 4-Oxo-4-((4-(pyridin-4-yl)thiazol-2-yl)amino)butanoic acid; Butanoic acid, 4-oxo-4-[(4-pyridin-4-yl-1,3-thiazol-2-yl)amino]-; 1328814-77-2; 4-(4-Pyridin-4-yl-1,3-thiazol-2-ylcarbamoyl)butanoic acid; 4-((4-(Pyridin-4-yl)thiazol-2-yl)carbamoyl)butanoic acid
EINECS	Contact for details

Quality Control

Every batch of 4-Oxo-4-[(4-Pyridin-4-Yl-1,3-Thiazol-2-Yl)Amino]Butanoic Acid is manufactured under strict quality management systems. Our products undergo rigorous analytical testing to ensure identity, purity, and consistency, meeting the stringent requirements for pharmaceutical research and development. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). The product may be hygroscopic (moisture-sensitive); keep the container tightly sealed when not in use to protect from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.