Description

Methyl 4-Bromo-2-Chloro-6-Fluorobenzoate is a high-purity, multi-halogenated benzoate ester serving as a critical advanced intermediate in modern organic synthesis. Its precise halogen substitution pattern makes it a valuable building block for constructing complex molecules with specific electronic and steric properties. This compound is primarily utilized by research institutions and industrial R&D departments in the pharmaceutical and agrochemical sectors for the development of new active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Building block for developing next-generation herbicides, fungicides, and insecticides, where the halogen atoms contribute to bioactivity and environmental stability.
• Material Science Research: Used in the creation of specialty polymers and liquid crystals, where the benzoate core and halogen substituents influence material properties.
• Chemical Biology & Proteomics: Serves as a scaffold or labeling agent in the design of molecular probes and enzyme inhibitors for biochemical research.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for use in custom synthesis projects and scale-up processes.

Basic Information

Product Name	Methyl 4-Bromo-2-Chloro-6-Fluorobenzoate
CAS No.	1321613-02-8
Molecular Formula	C8H5BrClFO2
Molecular Weight	267.48 g/mol
Synonyms	4-Bromo-2-chloro-6-fluorobenzoic acid methyl ester; Methyl 4-bromo-2-chloro-6-fluorobenzoate; Benzoic acid, 4-bromo-2-chloro-6-fluoro-, methyl ester; 2-Chloro-4-bromo-6-fluorobenzoic acid methyl ester; Methyl 2-chloro-4-bromo-6-fluorobenzoate
EINECS	Contact for details

Quality Control

Every batch of Methyl 4-Bromo-2-Chloro-6-Fluorobenzoate is manufactured under strict quality management systems. We provide comprehensive analytical documentation to ensure traceability and consistency for your critical R&D and scale-up work. A detailed Certificate of Analysis (COA) is supplied with each shipment, confirming identity, purity, and impurity profiles as determined by HPLC, GC, NMR, and other relevant spectroscopic methods.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. The compound may be light-sensitive; prolonged exposure to light should be avoided.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.