Description

2-Amino-3-Fluoro-5-Iodopyridine is a high-purity, multi-functional halogenated pyridine derivative, serving as a critical building block in advanced organic synthesis. Its unique structure, featuring amino, fluoro, and iodo substituents, makes it an exceptionally versatile intermediate for constructing complex molecular architectures. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly for kinase inhibitors, antiviral agents, and central nervous system (CNS) active compounds.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides, leveraging its halogenated pyridine core.
• Material Science Research: Serves as a functional monomer or ligand precursor for the development of specialty polymers, metal-organic frameworks (MOFs), and advanced catalytic systems.
• Cross-Coupling Reactions: The iodine substituent makes it an excellent substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Sonogashira) to create complex biaryl structures.
• Chemical Biology & Diagnostics: Employed as a scaffold for developing molecular probes, fluorescent tags, and other tools for biochemical research.

Basic Information

Product Name	2-Amino-3-Fluoro-5-Iodopyridine
CAS No.	1321612-85-4
Molecular Formula	C5H4FIN2
Molecular Weight	237.99 g/mol
Synonyms	3-Fluoro-5-iodopyridin-2-amine; 5-Iodo-3-fluoropyridin-2-amine; 2-Amino-3-fluoro-5-iodopyridine; 3-Fluoro-5-iodo-2-pyridinamine; 2-Pyridinamine, 3-fluoro-5-iodo-; 1321612-85-4; AI3-33166; SCHEMBL2180421
EINECS	Contact for details

Quality Control

Our 2-Amino-3-Fluoro-5-Iodopyridine is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with customer specifications and industry best practices for fine chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat and incompatible materials. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.