Description

2,6-Dichloro-5-(Trifluoromethyl)Nicotinonitrile is a high-value, multi-functional heterocyclic building block. This compound is critical for the synthesis of advanced pharmaceutical intermediates and agrochemicals due to its unique trifluoromethyl and chlorinated pyridine structure. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries to introduce key functional groups into target molecules.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in antiviral and anticancer research.
• Agrochemical Synthesis: Used in the manufacture of advanced herbicides and pesticides, where the trifluoromethyl group enhances biological activity and stability.
• Material Science Precursor: Serves as a building block for functionalized ligands and organic electronic materials.
• Cross-Coupling Reactions: The chlorine atoms provide reactive sites for versatile palladium-catalyzed coupling reactions (e.g., Suzuki, Buchwald-Hartwig).
• Fluorine Chemistry: Acts as a valuable source of the trifluoromethyl moiety for further fluorination and derivatization studies.
• Custom Synthesis & Contract Manufacturing: An essential starting material for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Product Name	2,6-Dichloro-5-(Trifluoromethyl)Nicotinonitrile
CAS No.	1319804-30-2
Molecular Formula	C7H1Cl2F3N2
Molecular Weight	241.00 g/mol
Synonyms	2,6-Dichloro-5-(trifluoromethyl)pyridine-3-carbonitrile; 5-Cyano-2,6-dichloro-3-(trifluoromethyl)pyridine; 3-Cyano-2,6-dichloro-5-(trifluoromethyl)pyridine; Nicotinonitrile, 2,6-dichloro-5-(trifluoromethyl)-; 2,6-Dichloro-5-trifluoromethylnicotinonitrile; Pyridine-3-carbonitrile, 2,6-dichloro-5-(trifluoromethyl)-
EINECS	Contact for details

Quality Control

Our 2,6-Dichloro-5-(Trifluoromethyl)Nicotinonitrile is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We adhere to cGMP principles where applicable, and our quality systems are designed to meet the stringent requirements of pharmaceutical and agrochemical customers.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture. Store away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.