Description

tert-Butyl 6-Oxo-2-Azaspiro[4.4]Nonane-2-Carboxylate (Wx101410) is a high-purity, advanced pharmaceutical intermediate featuring a unique spirocyclic scaffold. This compound is of significant value for medicinal chemistry research and development, serving as a critical building block for synthesizing novel active pharmaceutical ingredients (APIs). It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and biotechnology industries working on innovative drug candidates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug molecules, particularly those targeting neurological and metabolic disorders.
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Process Chemistry Development: Serves as a starting material or intermediate in the scale-up and optimization of API manufacturing routes.
• Protease Inhibitor Synthesis: The spirocyclic lactam structure is relevant for developing inhibitors of various proteolytic enzymes.
• Chemical Biology Probes: Can be utilized to create tool compounds for studying biological pathways and target engagement.
• Custom Synthesis: A building block for contract research and manufacturing organizations (CROs/CMOs) producing bespoke compounds for clients.

Basic Information

Product Name	tert-Butyl 6-Oxo-2-Azaspiro[4.4]Nonane-2-Carboxylate (Wx101410)
CAS No.	1319716-43-2
Molecular Formula	C13H21NO3
Molecular Weight	239.31 g/mol
Synonyms	2-Azaspiro[4.4]nonane-2-carboxylic acid, 6-oxo-, 1,1-dimethylethyl ester; 6-Oxo-2-azaspiro[4.4]nonane-2-carboxylic acid tert-butyl ester; tert-Butyl 6-oxo-2-azaspiro[4.4]nonane-2-carboxylate; WX-101410; WX101410; 2-tert-Butoxycarbonyl-6-oxo-2-azaspiro[4.4]nonane; 2-Boc-6-oxo-2-azaspiro[4.4]nonane
EINECS	Contact for details

Quality Control

Our tert-Butyl 6-Oxo-2-Azaspiro[4.4]Nonane-2-Carboxylate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specification results. Our quality commitment supports compliance with cGMP standards for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed and away from moisture and direct light exposure. For long-term storage, consider using desiccants and an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.