Description

2-Boc-7-Oxo-2-Azaspiro[4.4]Nonane is a high-purity, advanced pharmaceutical intermediate featuring a protected azaspirocyclic scaffold. This compound is a critical building block in the synthesis of complex molecules, offering a versatile handle for further functionalization in medicinal chemistry. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs) and drug candidates.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new therapeutic agents, particularly those targeting neurological and metabolic disorders.
• Medicinal Chemistry Research: Used as a core scaffold for constructing compound libraries in high-throughput screening and structure-activity relationship (SAR) studies.
• Process Chemistry Development: Serves as a starting material or intermediate in the scale-up and optimization of synthetic routes for potential drug substances.
• Protease Inhibitor Synthesis: The spirocyclic lactam structure is valuable in the design and synthesis of enzyme inhibitors.
• Academic Research: Employed in universities and research institutes for methodological studies in organic synthesis and heterocyclic chemistry.
• Contract Manufacturing (CDMO): Supplied to contract development and manufacturing organizations for custom synthesis projects.

Basic Information

Product Name	2-Boc-7-Oxo-2-Azaspiro[4.4]Nonane
CAS No.	1319716-42-1
Molecular Formula	C13H21NO4
Molecular Weight	255.31 g/mol
Synonyms	tert-Butyl 7-oxo-2-azaspiro[4.4]nonane-2-carboxylate; 2-(tert-Butoxycarbonyl)-2-azaspiro[4.4]nonan-7-one; 2-Boc-2-azaspiro[4.4]nonan-7-one; 2-Azaspiro[4.4]nonan-7-one, 2-[(1,1-dimethylethoxy)carbonyl]-; 2-tert-Butoxycarbonyl-2-azaspiro[4.4]nonan-7-one; 2-Boc-7-oxo-2-azaspiro[4.4]nonane; 2-Azaspiro[4.4]nonane-2-carboxylic acid, 7-oxo-, 1,1-dimethylethyl ester
EINECS	Contact for details

Quality Control

Our 2-Boc-7-Oxo-2-Azaspiro[4.4]Nonane is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical quality attributes. Our production adheres to cGMP guidelines where applicable, ensuring reliability for research and pre-clinical development phases.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed and may require storage under an inert atmosphere for long-term preservation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.