Description

3-Bromo-5-Cyclopropylpyridin-2-Amine is a high-purity, functionalized pyridine derivative of significant interest in advanced organic synthesis. This compound serves as a versatile and critical building block for constructing complex molecular architectures, particularly in pharmaceutical research and development. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, leveraging the biological activity of the pyridine and cyclopropyl motifs.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in transition metal catalysis and organocatalysis.
• Material Science Research: Employed in the synthesis of organic electronic materials, such as charge-transport layers or light-emitting components.
• Chemical Biology Probes: Utilized to create molecular probes for studying enzyme function and biological pathways due to its modifiable amine and halogen groups.
• Custom Synthesis and Contract Manufacturing: A fundamental substrate for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.

Basic Information

Product Name	3-Bromo-5-Cyclopropylpyridin-2-Amine
CAS No.	1319068-89-7
Molecular Formula	C8H9BrN2
Molecular Weight	213.08 g/mol
Synonyms	2-Amino-3-bromo-5-cyclopropylpyridine; 5-Cyclopropyl-3-bromopyridin-2-amine; 3-Bromo-5-cyclopropyl-2-pyridinamine; 1319068-89-7; 3-Bromo-5-cyclopropyl-2-aminopyridine
EINECS	Contact for details

Quality Control

Our 3-Bromo-5-Cyclopropylpyridin-2-Amine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.