Description

1-(2-Fluoropropyl)Piperidin-4-Amine Hydrochloride is a high-purity, pharmaceutically relevant intermediate characterized by its piperidine amine core functionalized with a fluoropropyl group. This compound matters as a critical building block in modern medicinal chemistry, enabling the synthesis of novel bioactive molecules with potential applications in central nervous system (CNS) and other therapeutic areas. It is primarily needed by research institutions, pharmaceutical development laboratories, and fine chemical manufacturers engaged in the discovery and production of new drug candidates.

Application

• Pharmaceutical Intermediate: Serves as a key synthetic precursor in the research and development of new active pharmaceutical ingredients (APIs), particularly for CNS-targeting drugs.
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and library synthesis to explore new chemical entities.
• Preclinical Development: Employed in the synthesis of compounds for pharmacological profiling, toxicology studies, and early-stage drug candidate optimization.
• Reference Standard: Can be utilized as an analytical standard for method development and quality control in regulatory filings for novel therapeutics.
• Chemical Biology Probe Synthesis: Acts as a building block for creating molecular probes to study biological pathways and protein interactions.

Basic Information

Product Name	1-(2-Fluoropropyl)Piperidin-4-Amine Hydrochloride
CAS No.	1315499-89-8
Molecular Formula	C8H18ClFN2
Molecular Weight	196.69 g/mol (Free base: 160.24 g/mol)
Synonyms	4-Amino-1-(2-fluoropropyl)piperidine hydrochloride; 1-(2-Fluoropropyl)-4-piperidinamine hydrochloride; 4-Piperidinamine, 1-(2-fluoropropyl)-, hydrochloride; N-(2-Fluoropropyl)-4-aminopiperidine hydrochloride; 1-(2-Fluoropropyl)piperidin-4-amine HCl; 4-Amino-1-(2-fluoropropyl)piperidine HCl salt
EINECS	Contact for details

Quality Control

Our 1-(2-Fluoropropyl)Piperidin-4-Amine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency, meeting the high standards required for pharmaceutical research and development. A comprehensive Certificate of Analysis (COA) detailing purity (typically ≥95% by HPLC), identity confirmation (by IR, NMR, and MS), and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.