Description

5-Ethenyl-4-Methoxy-1-[[2-(Trimethylsilyl)Ethoxy]Methyl]-1H-Pyrrolo[2,3-B]Pyridine CAS NO 1315466-96-6 is a sophisticated, multi-functional heterocyclic building block featuring a silyl-protected hydroxymethyl group and a reactive ethenyl moiety. This compound is of critical importance in modern pharmaceutical and agrochemical research, serving as a versatile intermediate for the synthesis of complex molecules, particularly kinase inhibitors and other biologically active scaffolds. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, biotechnology, and advanced material sectors.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel kinase inhibitors and other targeted therapeutic agents.
• Agrochemical Research: Used in developing advanced active ingredients for crop protection with specific modes of action.
• Chemical Biology: Serves as a probe or linker in the development of chemical tools for studying biological pathways.
• Material Science: Potential precursor for functionalized organic semiconductors or ligands in catalytic systems.
• Process Chemistry: Employed in route scouting and optimization for the scalable production of complex APIs.
• Custom Synthesis: Starting material for contract research organizations (CROs) and CDMOs offering bespoke chemical services.

Basic Information

Product Name	5-Ethenyl-4-Methoxy-1-[[2-(Trimethylsilyl)Ethoxy]Methyl]-1H-Pyrrolo[2,3-B]Pyridine
CAS No.	1315466-96-6
Molecular Formula	C16H24N2O2Si
Molecular Weight	304.46 g/mol
Synonyms	1-((2-(Trimethylsilyl)ethoxy)methyl)-5-vinyl-4-methoxy-1H-pyrrolo[2,3-b]pyridine; 4-Methoxy-5-vinyl-1-((2-(trimethylsilyl)ethoxy)methyl)-1H-pyrrolo[2,3-b]pyridine; 5-Vinyl-4-methoxy-1-((2-(trimethylsilyl)ethoxy)methyl)-1H-pyrrolo[2,3-b]pyridine; 1H-Pyrrolo[2,3-b]pyridine, 5-ethenyl-4-methoxy-1-[[2-(trimethylsilyl)ethoxy]methyl]-; SEM-protected 5-vinyl-4-methoxy-7-azaindole
EINECS	Contact for details

Quality Control

Our 5-Ethenyl-4-Methoxy-1-[[2-(Trimethylsilyl)Ethoxy]Methyl]-1H-Pyrrolo[2,3-B]Pyridine is produced under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with each shipment. We can support development projects with material meeting >95% to >98% purity standards, with custom purity grades available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0% (Standard Grade)
Purity (HPLC)	≥ 98.0% (High Purity Grade)
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.