Description

2-Chloro-5-(Difluoromethoxy)-3-Methylpyridine is a high-purity, advanced pharmaceutical intermediate characterized by its unique halogenated pyridine structure. This compound is of significant commercial importance for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily sought after by research institutions and manufacturers in the agrochemical and pharmaceutical sectors for developing next-generation products.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly in medicinal chemistry programs.
• Agrochemical Synthesis: Serves as a crucial precursor for the manufacture of modern pesticides and herbicides, leveraging its difluoromethoxy and chloro substituents.
• Chemical Research: Used in academic and industrial R&D for exploring novel heterocyclic compounds and reaction pathways.
• Material Science: Potential application as a building block for specialty chemicals and functional materials.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects.

Basic Information

Product Name	2-Chloro-5-(Difluoromethoxy)-3-Methylpyridine
CAS No.	1315360-83-8
Molecular Formula	C7H6ClF2NO
Molecular Weight	193.58 g/mol
Synonyms	3-Methyl-2-chloro-5-(difluoromethoxy)pyridine; 2-Chloro-3-methyl-5-(difluoromethoxy)pyridine; 5-(Difluoromethoxy)-2-chloro-3-methylpyridine; Pyridine, 2-chloro-5-(difluoromethoxy)-3-methyl-; CAS 1315360-83-8
EINECS	Contact for details

Quality Control

Our 2-Chloro-5-(Difluoromethoxy)-3-Methylpyridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and consistency. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong bases and oxidizing agents. For long-term storage, consider under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.