Description

2,3-Dimethyl-7-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-2H-Indazole is a high-value, functionalized indazole derivative containing a pinacol boronate ester group. This compound is a critical synthetic intermediate, prized for its role in enabling efficient carbon-carbon bond formation via cross-coupling reactions. It is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and complex molecular scaffolds.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of drug candidates, particularly in medicinal chemistry for creating libraries of indazole-based compounds.
• Suzuki-Miyaura Cross-Coupling Reactions: Serves as a versatile boronic ester reagent for coupling with aryl/heteroaryl halides to construct biaryl and heterobiaryl structures.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides that incorporate the indazole pharmacophore.
• Material Science: Potential precursor for organic electronic materials and ligands in catalytic systems.
• Chemical Biology: Useful as a probe or tag in bioconjugation chemistry due to its reactive boronate functionality.
• Process Chemistry & Scale-up: Employed in route development and optimization for the commercial production of target molecules.

Basic Information

Product Name	2,3-Dimethyl-7-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-2H-Indazole
CAS No.	1315335-64-8
Molecular Formula	C₁₅H₂₁BN₂O₂
Molecular Weight	272.15 g/mol
Synonyms	7-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-2,3-dimethyl-2H-indazole; 2,3-Dimethyl-7-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indazole; 2,3-Dimethyl-7-(pinacolboron)-2H-indazole; 7-Pinacolatoboryl-2,3-dimethyl-2H-indazole; 1315335-64-8; 2H-Indazole, 2,3-dimethyl-7-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-
EINECS	Contact for details

Quality Control

Our 2,3-Dimethyl-7-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-2H-Indazole is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity for research and development applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We support cGMP compliance for advanced intermediates and can provide material to meet specific customer protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). The compound is light-sensitive and should be handled under an inert atmosphere for prolonged manipulations to ensure stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥97.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Single Unknown Impurity (HPLC)	≤0.5%
Total Impurities (HPLC)	≤2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.