Description

(S)-Hydroxy-2,4-Dimethyl-Pentanoic Acid is a chiral, non-natural hydroxy acid of significant interest in advanced organic synthesis. Its value lies in its role as a versatile building block for constructing complex molecules with defined stereochemistry, which is critical for developing active pharmaceutical ingredients and specialty chemicals. This compound is primarily needed by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and fine chemical sectors for applications requiring high enantiomeric purity.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting metabolic and central nervous system disorders.
• Agrochemical Synthesis: Used in the research and development of novel, enantiomerically pure herbicides, fungicides, and plant growth regulators.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals, flavors, and fragrances where specific stereochemistry is required.
• Peptidomimetics Research: Acts as a constrained, non-proteinogenic amino acid analog in the design of peptide-based therapeutics and biochemical probes.
• Material Science: Investigated as a monomer or cross-linking agent for producing polymers with tailored properties.

Basic Information

Item	Details
Product Name	(S)-Hydroxy-2,4-Dimethyl-Pentanoic Acid
CAS No.	1315051-00-3
Molecular Formula	C7H14O3
Molecular Weight	146.18 g/mol
Synonyms	(S)-2-Hydroxy-2,4-dimethylpentanoic acid; (2S)-2-Hydroxy-2,4-dimethylpentanoic acid; L-2-Hydroxy-2,4-dimethylvaleric acid; (S)-2,4-Dimethyl-2-hydroxypentanoic acid; (S)-HMPA; (S)-2-Hydroxy-2,4-dimethylvaleric acid
EINECS	Contact for details

Quality Control

Our (S)-Hydroxy-2,4-Dimethyl-Pentanoic Acid is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral HPLC for enantiomeric excess (ee) verification, to ensure compliance with high-purity standards for research and industrial use. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) in its original packaging to prevent degradation upon exposure to air and humidity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.