Description

5-(3-Chloro-4-Fluorophenyl)Pyridin-2-Amine is a high-purity, halogenated pyridine derivative serving as a critical building block in advanced organic synthesis. This compound is valued for its role as a key intermediate in the development of active pharmaceutical ingredients (APIs) and agrochemicals, where its specific substitution pattern enables precise molecular design. It is primarily sought by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for creating novel compounds with targeted biological activity.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of novel drug candidates, particularly in kinase inhibitor and other small-molecule therapeutic programs.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides, leveraging its halogenated aromatic structure.
• Material Science Research: Serves as a precursor for functionalized ligands and organic electronic materials due to its pyridine core.
• Chemical Biology: Employed as a molecular probe or scaffold in medicinal chemistry and biochemical research.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for bespoke synthesis projects.

Basic Information

Product Name	5-(3-Chloro-4-Fluorophenyl)Pyridin-2-Amine
CAS No.	1314985-70-0
Molecular Formula	C11H8ClFN2
Molecular Weight	222.65 g/mol
Synonyms	5-(3-Chloro-4-fluorophenyl)-2-pyridinamine; 2-Amino-5-(3-chloro-4-fluorophenyl)pyridine; 5-(3-Chloro-4-fluorophenyl)pyridin-2-amine; 1314985-70-0; 5-(3-Chloro-4-fluoro-phenyl)-pyridin-2-ylamine; 2-Pyridinamine, 5-(3-chloro-4-fluorophenyl)-
EINECS	Contact for details

Quality Control

Our 5-(3-Chloro-4-Fluorophenyl)Pyridin-2-Amine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with agreed specifications. Our quality commitment supports applications requiring GMP-grade intermediates and research-grade materials.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials. The container should be kept tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.