Description

1-Boc-3-Methylazetidine is a high-purity, protected azetidine derivative, serving as a critical building block in advanced organic synthesis. Its value lies in providing a versatile and reactive nitrogen-containing scaffold for constructing complex molecular architectures. This compound is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of drug candidates, particularly those targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Synthesis: Used in the development of novel pesticides and herbicides, leveraging the azetidine ring's bioactivity.
• Peptidomimetics & Bioisosteres: The protected amine functionality is essential for creating conformationally restricted peptide analogs and bioisosteric replacements in medicinal chemistry.
• Ligand & Catalyst Development: Serves as a starting material for synthesizing specialized ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the development of novel polymers and functional materials with tailored properties.
• Custom Synthesis & Contract Manufacturing: A fundamental reagent for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) producing bespoke compounds for clients.

Basic Information

Product Name	1-Boc-3-Methylazetidine
CAS No.	1314984-00-3
Molecular Formula	C9H17NO2
Molecular Weight	171.24 g/mol
Synonyms	3-Methylazetidine-1-carboxylic acid tert-butyl ester; tert-Butyl 3-methylazetidine-1-carboxylate; 1-(tert-Butoxycarbonyl)-3-methylazetidine; 3-Methyl-1-Boc-azetidine; N-Boc-3-methylazetidine; Azetidine, 3-methyl-, 1-(1,1-dimethylethyl) ester; Boc-3-methylazetidine
EINECS	Contact for details

Quality Control

Our 1-Boc-3-Methylazetidine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and identity. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment. We adhere to cGMP principles where applicable to support our clients' regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which can compromise product integrity. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.