Description

7'-Bromo-2',3'-dihydro-1'H-spiro[cyclobutane-1,4'-isoquinoline] is a high-value, advanced pharmaceutical intermediate characterized by its unique spirocyclic and brominated isoquinoline structure. This compound is critical for medicinal chemistry research and development, serving as a versatile building block for the synthesis of novel bioactive molecules. It is primarily sought after by R&D teams in the pharmaceutical, agrochemical, and fine chemical industries for creating new drug candidates and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential therapeutic agents targeting central nervous system (CNS) disorders, oncology, and other disease areas.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• Agrochemical Development: Serves as a building block for creating novel active ingredients in crop protection research.
• Fine Chemical Synthesis: Employed in the multi-step synthesis of complex, high-value specialty chemicals and functional materials.
• Academic & Contract Research: Utilized in university and CRO laboratories for exploratory synthetic chemistry and methodological development.

Basic Information

Product Name	7'-Bromo-2',3'-dihydro-1'H-spiro[cyclobutane-1,4'-isoquinoline]
CAS No.	1314792-82-9
Molecular Formula	C13H14BrN
Molecular Weight	264.16 g/mol
Synonyms	7'-Bromospiro[cyclobutane-1,4'-isoquinoline]; 1'H-Spiro[cyclobutane-1,4'-isoquinoline], 7'-bromo-2',3'-dihydro-; 7'-Bromo-1'H-spiro[cyclobutane-1,4'-isoquinoline]; 7-Bromo-2,3-dihydro-1H-spiro[isoquinoline-4,1'-cyclobutane]; Spiro[cyclobutane-1,4'-isoquinoline], 7'-bromo-2',3'-dihydro-1'H-; 1314792-82-9
EINECS	Contact for details

Quality Control

Our production of 7'-Bromo-2',3'-dihydro-1'H-spiro[cyclobutane-1,4'-isoquinoline] adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with customer specifications and supporting regulatory filings for research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥97.0%
Related Substances (HPLC)	Individual impurity ≤1.0%; Total impurities ≤3.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.