Description

6'-Bromo-2',3'-Dihydro-1'H-Spiro[Cyclobutane-1,4'-Isoquinoline] CAS NO 1314756-12-1 is a high-value, spirocyclic organic building block featuring a brominated isoquinoline scaffold fused to a cyclobutane ring. This compound is of significant interest for its structural complexity and functional handle, making it a critical intermediate in advanced synthetic chemistry. It is primarily sought after by pharmaceutical and agrochemical research organizations for the development of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of potential drug candidates, particularly for central nervous system (CNS) targets and kinase inhibitors.
• Agrochemical Research: Used in the discovery and development of new herbicides, fungicides, and insecticides due to its bioactive scaffold.
• Chemical Biology Probe: Employed as a molecular tool to study enzyme function and protein-ligand interactions in biological systems.
• Material Science: Acts as a building block for creating novel organic semiconductors, ligands for catalysis, or components for advanced polymers.
• Academic & Contract Research: Utilized in universities and CROs for methodological development and exploration of new chemical spaces in synthetic organic chemistry.

Basic Information

Product Name	6'-Bromo-2',3'-Dihydro-1'H-Spiro[Cyclobutane-1,4'-Isoquinoline]
CAS No.	1314756-12-1
Molecular Formula	C13H14BrN
Molecular Weight	264.16 g/mol
Synonyms	6'-Bromospiro[cyclobutane-1,4'-isoquinoline]; 6'-Bromo-1'H-spiro[cyclobutane-1,4'-isoquinoline]; 6'-Bromo-2',3'-dihydrospiro[cyclobutane-1,4'-isoquinoline]; Spiro[cyclobutane-1,4'-isoquinoline], 6'-bromo-2',3'-dihydro-; 6-Bromospiro[cyclobutane-1,4(1'H)-isoquinoline]; 1314756-12-1; AKOS040759830; FT-0774839
EINECS	Contact for details

Quality Control

Our production of 6'-Bromo-2',3'-Dihydro-1'H-Spiro[Cyclobutane-1,4'-Isoquinoline] adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical characterization, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with agreed specifications. We support cGMP and ISO 9001 standards for research and development materials.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.