Description

Ethyl (R)-1-Boc-3-pyrrolidinecarboxylate is a high-purity chiral building block and advanced pharmaceutical intermediate. This compound is critical for the synthesis of complex molecules, offering precise stereochemical control essential for developing active pharmaceutical ingredients (APIs). It is primarily utilized by research institutions and manufacturers in the pharmaceutical, agrochemical, and fine chemical sectors for constructing pyrrolidine-based scaffolds.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the asymmetric synthesis of drug candidates, particularly those targeting central nervous system (CNS) disorders.
• API Development: Used in the research and production of Active Pharmaceutical Ingredients (APIs) that require the (R)-configured pyrrolidine moiety.
• Agrochemical Synthesis: Serves as a building block for creating novel, stereospecific agrochemicals and pesticides.
• Catalyst Ligand Precursor: Employed in the preparation of chiral ligands for asymmetric catalysis and metal-organic frameworks.
• Academic & Industrial R&D: A valuable reagent for method development and exploratory chemistry in medicinal and synthetic chemistry laboratories.
• Fine Chemical Production: Integral to the multi-step synthesis of complex, high-value specialty chemicals and flavors/fragrances.

Basic Information

Product Name	Ethyl (R)-1-Boc-3-pyrrolidinecarboxylate
CAS No.	1314419-65-2
Molecular Formula	C12H21NO4
Molecular Weight	243.30 g/mol
Synonyms	1-Boc-3-(ethoxycarbonyl)-(R)-pyrrolidine; (R)-1-(tert-Butoxycarbonyl)-3-pyrrolidinecarboxylic acid ethyl ester; Ethyl (R)-1-(tert-butoxycarbonyl)-3-pyrrolidinecarboxylate; (R)-1-Boc-3-pyrrolidinecarboxylic acid ethyl ester; (R)-N-Boc-3-pyrrolidinecarboxylic acid ethyl ester; tert-Butyl (R)-3-(ethoxycarbonyl)pyrrolidine-1-carboxylate; (R)-1-Boc-pyrrolidine-3-carboxylic acid ethyl ester
EINECS	Contact for details

Quality Control

Our Ethyl (R)-1-Boc-3-pyrrolidinecarboxylate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity assessment by HPLC, to ensure it meets the high standards required for pharmaceutical development. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request to support your regulatory and quality assurance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This material is moisture-sensitive (hygroscopic); keep the container tightly sealed under an inert atmosphere if necessary.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.