Description

5-Hydroxy-2-Methyl-Piperidine-1-Carboxylic Acid Benzyl Ester CAS NO 1314396-07-0 is a high-purity, functionalized piperidine derivative that serves as a critical chiral building block and intermediate in advanced organic synthesis. Its value lies in its unique molecular scaffold, which incorporates both a protected carboxylic acid and a hydroxyl group, enabling precise chemical modifications for complex molecule construction. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for the synthesis of active pharmaceutical ingredients (APIs), novel drug candidates, and specialized fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of novel therapeutic agents, including central nervous system (CNS) drugs and enzyme inhibitors.
• Agrochemical Synthesis: Used in the creation of advanced, targeted pesticides and herbicides where specific stereochemistry is required for biological activity.
• Catalyst and Ligand Development: Serves as a precursor for synthesizing novel chiral ligands and organocatalysts used in asymmetric synthesis.
• Fine Chemical Production: Employed in the multi-step synthesis of complex, high-value specialty chemicals and flavors & fragrances.
• Academic and R&D Laboratories: A valuable reagent for methodological studies in organic chemistry, particularly in exploring new C-N and C-O bond-forming reactions.
• Peptidomimetic Research: The piperidine core makes it a useful scaffold for designing and synthesizing peptide mimics for drug discovery programs.

Basic Information

Product Name	5-Hydroxy-2-Methyl-Piperidine-1-Carboxylic Acid Benzyl Ester
CAS No.	1314396-07-0
Molecular Formula	C14H19NO3
Molecular Weight	249.31 g/mol
Synonyms	Benzyl 5-hydroxy-2-methylpiperidine-1-carboxylate; 1-Carbobenzyloxy-5-hydroxy-2-methylpiperidine; 2-Methyl-5-hydroxypiperidine-1-carboxylic acid benzyl ester; 1-N-CBZ-5-Hydroxy-2-methylpiperidine; 5-Hydroxy-2-methyl-1-piperidinecarboxylic acid phenylmethyl ester; 1-(Benzyloxycarbonyl)-5-hydroxy-2-methylpiperidine; 2-Methyl-5-hydroxypiperidine-1-N-carboxybenzyl ester
EINECS	Contact for details

Quality Control

Our 5-Hydroxy-2-Methyl-Piperidine-1-Carboxylic Acid Benzyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and chiral purity analysis, to ensure it meets the high standards required for research and commercial synthesis. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment. We can support development projects with custom purity grades and analytical method development upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This compound may be hygroscopic (moisture-sensitive); therefore, the container should be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.