Description

Bis-Peg2-Pfp Ester CAS NO 1314378-18-1 is a specialized bifunctional PEG linker featuring pentafluorophenyl (Pfp) ester groups. This compound is a critical reagent in bioconjugation and pharmaceutical development, enabling efficient and selective coupling of molecules under mild conditions. It is primarily utilized by researchers and manufacturers in the fields of biopharmaceuticals, proteomics, and advanced material science for constructing complex molecular architectures.

Application

• Bioconjugation Reagent: For the site-specific modification of peptides, proteins, and antibodies.
• Pharmaceutical Linker: In the synthesis of antibody-drug conjugates (ADCs) and other targeted therapeutics.
• Crosslinking Agent: For creating hydrogels, polymer networks, and functionalized surfaces in material science.
• Proteomics Research: As a tool for labeling and immobilizing biomolecules for analysis.
• Diagnostic Reagent Synthesis: In the development of contrast agents and molecular probes.
• Polymer Functionalization: To introduce reactive handles onto polymer backbones for further chemical modification.

Basic Information

Product Name	Bis-Peg2-Pfp Ester
CAS No.	1314378-18-1
Molecular Formula	C22H18F10O8
Molecular Weight	612.37 g/mol
Synonyms	1,11-Bis(2,3,4,5,6-pentafluorophenoxy)-3,6,9-trioxaundecane; Bis(PEG2) pentafluorophenyl ester; α,ω-Bis(pentafluorophenyl) PEG2 diester; PFP-PEG2-PFP; PEG2 bis(pentafluorophenyl) ester; Bifunctional PEG2-PFP crosslinker; 3,6-Dioxaoctanedioic acid bis(2,3,4,5,6-pentafluorophenyl) ester
EINECS	Contact for details

Quality Control

Our Bis-Peg2-Pfp Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high purity and batch-to-batch consistency. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment to support your research and development needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a freezer at -20°C or below under desiccant. This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent hydrolysis of the active ester groups.

Specification

Item	Specification
Appearance	White to off-white solid or oil
Identification (HPLC/MS)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 0.5%
Solubility	Soluble in DMF, DMSO, acetonitrile

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.