Description

4-Bromo-3-Cyclopropylpyridine is a high-value brominated pyridine derivative that serves as a critical building block in advanced organic synthesis. Its unique structure, combining a cyclopropyl group with a halogenated pyridine ring, makes it an essential intermediate for constructing complex molecular architectures. This compound is primarily utilized by research and development chemists in the pharmaceutical and agrochemical industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and anti-infective agents.
• Agrochemical Synthesis: Used in the development of new-generation herbicides, fungicides, and insecticides, where the cyclopropyl moiety can enhance biological activity and stability.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands in transition metal catalysis and organocatalysis.
• Material Science Research: Employed in the synthesis of organic electronic materials, such as components for OLEDs or conductive polymers.
• Chemical Biology Probes: Useful for constructing molecular probes and tags used in biochemical assay development and diagnostic research.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific custom synthesis projects.

Basic Information

Product Name	4-Bromo-3-Cyclopropylpyridine
CAS No.	1314355-04-8
Molecular Formula	C8H8BrN
Molecular Weight	198.06 g/mol
Synonyms	3-Cyclopropyl-4-bromopyridine; 4-Bromo-3-cyclopropyl-pyridine; Pyridine, 4-bromo-3-cyclopropyl-; 4-Bromo-3-cyclopropylpyridine; 1314355-04-8
EINECS	Contact for details

Quality Control

Our 4-Bromo-3-Cyclopropylpyridine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, documenting all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for research and scale-up activities.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound is light-sensitive; prolonged exposure to light should be avoided.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Residual Solvents (GC)	Meets ICH guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.