Description

4-Bromo-3-Cyclobutylpyridine is a high-purity, advanced pharmaceutical intermediate and versatile building block in organic synthesis. This compound is valued for its unique molecular architecture, which combines a brominated pyridine core with a strained cyclobutyl substituent, enabling precise functionalization for complex molecule construction. It is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries to develop novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly for kinase inhibitors and other small molecule therapeutics.
• Agrochemical Synthesis: Serves as a building block for creating novel pesticides, herbicides, and plant growth regulators with enhanced efficacy.
• Ligand & Catalyst Development: Used in the design and synthesis of specialized ligands for transition metal catalysis and organocatalysts.
• Material Science Research: Employed in the development of organic electronic materials, such as charge-transport layers or photoactive components.
• Chemical Biology Probes: Acts as a precursor for labeled compounds or molecular probes used in biochemical and cellular assay development.
• Cross-Coupling Reactions: The bromine atom makes it an excellent substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to form biaryl structures.

Basic Information

Product Name	4-Bromo-3-Cyclobutylpyridine
CAS No.	1314353-64-4
Molecular Formula	C9H10BrN
Molecular Weight	212.09 g/mol
Synonyms	3-Cyclobutyl-4-bromopyridine; 4-Bromo-3-cyclobutylpyridine; Pyridine, 4-bromo-3-cyclobutyl-; 1314353-64-4
EINECS	Contact for details

Quality Control

Our 4-Bromo-3-Cyclobutylpyridine is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with customer specifications and industry best practices for research-grade chemicals.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The product is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.