Description

2-Hydroxymethylpyridine-4-Boronic Acid Pinacol Ester is a high-value, multi-functional boronic ester derivative crucial for modern synthetic chemistry. This compound matters as a key building block in cross-coupling reactions, enabling the efficient construction of complex molecules for advanced material and pharmaceutical research. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for creating novel active ingredients and functional polymers.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A critical reagent for forming carbon-carbon bonds in the synthesis of biaryl and heterobiaryl structures.
• Pharmaceutical Intermediate: Used in the research and development of active pharmaceutical ingredients (APIs), particularly those containing pyridine motifs.
• Agrochemical Synthesis: Serves as a building block for creating novel herbicides, fungicides, and insecticides.
• Material Science & OLED Development: Employed in the synthesis of organic ligands for metal-organic frameworks (MOFs) and electron-transport materials for organic light-emitting diodes (OLEDs).
• Chemical Biology & Probe Development: Utilized for modifying biomolecules and creating fluorescent or affinity probes for biological target identification.
• Polymer Chemistry: Acts as a monomer or chain extender in the synthesis of specialty polymers with tailored properties.

Basic Information

Product Name	2-Hydroxymethylpyridine-4-Boronic Acid Pinacol Ester
CAS No.	1314135-84-6
Molecular Formula	C13H20BNO3
Molecular Weight	249.12 g/mol
Synonyms	4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-2-pyridinemethanol; 2-(Hydroxymethyl)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine; (2-(Hydroxymethyl)pyridin-4-yl)boronic acid pinacol ester; 2-Pyridinemethanol, 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-; 4-Boronic acid pinacol ester-2-hydroxymethylpyridine
EINECS	Contact for details

Quality Control

Every batch of our 2-Hydroxymethylpyridine-4-Boronic Acid Pinacol Ester is produced and tested under strict quality management systems to ensure consistency and reliability for your critical syntheses. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as purity (HPLC/NMR), identity (IR, NMR), and impurity profiles. Our quality commitment aligns with cGMP principles for advanced intermediates, supporting regulatory filings.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (argon or nitrogen) after opening to prevent moisture absorption and decomposition. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.