Description

tert-Butyl (1-(4-(2-(2-Aminopyridin-3-Yl)-5-Phenyl-3H-Imidazo[4,5-B]Pyridin-3-Yl)Phenyl)Cyclobutyl)Carbamate is a sophisticated heterocyclic organic compound featuring a complex fused imidazopyridine core. This high-purity intermediate is of significant value in pharmaceutical research and development, particularly for its role as a key building block in the synthesis of targeted therapeutic agents. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical and biotechnology industries for creating novel drug candidates.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of novel small-molecule drug candidates, particularly kinase inhibitors and other targeted therapies.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies to develop compounds with improved potency and selectivity.
• Process Chemistry Development: Serves as a key intermediate for scaling up synthetic routes from laboratory to pilot plant and commercial manufacturing.
• Biochemical Probe Development: Can be utilized to create tool compounds for investigating specific biological pathways and target validation.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of client-specific advanced intermediates.
• Academic Research: Used in university and institutional labs for cutting-edge research in organic synthesis and drug discovery methodologies.

Basic Information

Product Name	tert-Butyl (1-(4-(2-(2-Aminopyridin-3-Yl)-5-Phenyl-3H-Imidazo[4,5-B]Pyridin-3-Yl)Phenyl)Cyclobutyl)Carbamate
CAS No.	1313881-69-4
Molecular Formula	C32H30N6O2
Molecular Weight	530.62 g/mol
Synonyms	1,1-Dimethylethyl N-[1-[4-[2-(2-amino-3-pyridinyl)-5-phenyl-3H-imidazo[4,5-b]pyridin-3-yl]phenyl]cyclobutyl]carbamate; tert-Butyl (1-(4-(2-(2-aminopyridin-3-yl)-5-phenyl-3H-imidazo[4,5-b]pyridin-3-yl)phenyl)cyclobutyl)carbamate; BOC-protected imidazopyridine amine; 1313881-69-4; (1-(4-(2-(2-Aminopyridin-3-yl)-5-phenyl-3H-imidazo[4,5-b]pyridin-3-yl)phenyl)cyclobutyl)carbamic acid tert-butyl ester
EINECS	Contact for details

Quality Control

Our tert-Butyl (1-(4-(2-(2-Aminopyridin-3-Yl)-5-Phenyl-3H-Imidazo[4,5-B]Pyridin-3-Yl)Phenyl)Cyclobutyl)Carbamate is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and development. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We adhere to ICH guidelines for stability and impurity characterization, supporting regulatory filings.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when appropriate to prevent degradation. Keep the container tightly sealed in a desiccator for long-term storage.

Specification

Item	Specification
Appearance	Off-white to light yellow solid
Identification (HPLC)	Conforms
Identification (IR)	Conforms to reference spectrum
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.