Description

3-Hydroxy-4,5,6,7-tetrahydro-2H-pyrazolo[3,4-c]pyridin-5-carboxylic acid hydrochloride is a high-purity heterocyclic building block and pharmaceutical intermediate of significant commercial interest. Its value lies in its complex fused pyrazolopyridine scaffold, which is a privileged structure in medicinal chemistry for the development of novel therapeutics. This compound is primarily sought by research institutions and pharmaceutical companies engaged in the synthesis of active pharmaceutical ingredients (APIs) and drug discovery programs targeting a range of central nervous system and metabolic disorders.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the multi-step synthesis of novel drug candidates, particularly those targeting kinase inhibition.
• Medicinal Chemistry Research: Used as a versatile scaffold for constructing compound libraries in high-throughput screening and structure-activity relationship (SAR) studies.
• Active Pharmaceutical Ingredient (API) Development: Employed in the research and process development stages for potential new chemical entities (NCEs).
• Biochemical Tool Compound: May be utilized in biochemical assays to study specific enzyme pathways and biological mechanisms.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and scale-up services for the life sciences industry.

Basic Information

Product Name	3-Hydroxy-4,5,6,7-tetrahydro-2H-pyrazolo[3,4-c]pyridin-5-carboxylic acid hydrochloride
CAS No.	1313739-01-3
Molecular Formula	C8H12ClN3O3
Molecular Weight	233.65 g/mol
Synonyms	5-Carboxy-3-hydroxy-4,5,6,7-tetrahydro-2H-pyrazolo[3,4-c]pyridine hydrochloride; 3-Hydroxy-4,5,6,7-tetrahydro-2H-pyrazolo[3,4-c]pyridine-5-carboxylic acid HCl; 2H-Pyrazolo[3,4-c]pyridine-5-carboxylic acid, 3-hydroxy-4,5,6,7-tetrahydro-, hydrochloride; Pyrazolopyridine-5-carboxylic acid derivative HCl salt
EINECS	Contact for details

Quality Control

Our 3-Hydroxy-4,5,6,7-tetrahydro-2H-pyrazolo[3,4-c]pyridin-5-carboxylic acid hydrochloride is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the stringent requirements for pharmaceutical R&D. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting batch-specific results.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.