Description

tert-Butyl 3-nitropiperidin-1-carboxylate is a high-purity, protected piperidine derivative serving as a critical building block in advanced organic synthesis. This compound is valued for its role in constructing complex nitrogen-containing heterocycles, which are central to modern pharmaceutical discovery and agrochemical development. It is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for the synthesis of novel active ingredients and intermediates.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel piperidine-based drug candidates, including potential kinase inhibitors, receptor modulators, and central nervous system (CNS) active compounds.
• Agrochemical Synthesis: Used in the research and production of advanced crop protection agents and pesticides that incorporate functionalized piperidine scaffolds.
• Chemical Biology & Proteomics: Serves as a versatile scaffold for creating molecular probes, activity-based probes (ABPs), and tagged compounds for target identification and validation studies.
• Medicinal Chemistry Research: Enables structure-activity relationship (SAR) exploration and lead optimization campaigns by providing a modifiable nitro-functionalized piperidine core.
• Custom Synthesis & Contract Manufacturing: An essential starting material for custom synthesis providers and CDMOs (Contract Development and Manufacturing Organizations) producing bespoke intermediates for client projects.
• Academic Research: Employed in university and institutional laboratories for methodological development in organic synthesis and heterocyclic chemistry.

Basic Information

Product Name	tert-Butyl 3-nitropiperidin-1-carboxylate
CAS No.	1313738-96-3
Molecular Formula	C10H18N2O4
Molecular Weight	230.26 g/mol
Synonyms	1-Boc-3-nitropiperidine; tert-Butyl 3-nitro-1-piperidinecarboxylate; 3-Nitro-1-piperidinecarboxylic acid tert-butyl ester; 1-(tert-Butoxycarbonyl)-3-nitropiperidine; 3-Nitropiperidine-1-carboxylic acid tert-butyl ester; N-Boc-3-nitropiperidine; Boc-3-nitropiperidine; 1-N-Boc-3-nitropiperidine
EINECS	Contact for details

Quality Control

Every batch of tert-Butyl 3-nitropiperidin-1-carboxylate is manufactured and tested under a strict quality management system to ensure consistency and reliability for your critical research and development processes. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request and are provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed and stored under dry, inert conditions to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.