Description

3,4,8-Trichloro-1,7-Naphthyridine CAS NO 1313738-65-6 is a high-purity halogenated naphthyridine derivative serving as a critical advanced intermediate in modern synthetic chemistry. Its value lies in providing a versatile, functionalized scaffold for constructing complex molecular architectures, particularly in pharmaceutical and agrochemical research. This compound is essential for R&D chemists and process development scientists in the life sciences sector who require reliable, high-quality building blocks for drug discovery and material science applications.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel active pharmaceutical ingredients (APIs), especially in kinase inhibitor and antiviral drug discovery programs.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and pesticides, leveraging its halogenated heterocyclic core.
• Material Science Precursor: Serves as a monomer or functional unit in the creation of organic electronic materials, such as semiconductors and light-emitting compounds.
• Chemical Biology Probe: Utilized in medicinal chemistry for structure-activity relationship (SAR) studies and as a molecular scaffold in probe design.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) producing specialized fine chemicals.
• Academic & Industrial R&D: Fundamental research reagent in universities and corporate labs for exploring new heterocyclic chemistry and reaction methodologies.

Basic Information

Product Name	3,4,8-Trichloro-1,7-Naphthyridine
CAS No.	1313738-65-6
Molecular Formula	C8H3Cl3N2
Molecular Weight	233.48 g/mol
Synonyms	1,7-Naphthyridine, 3,4,8-trichloro-; 3,4,8-Trichloro-1,7-naphthyridine; Trichloro-1,7-naphthyridine; 3,4,8-Trichloro[1,7]naphthyridine; 1313738-65-6; 3,4,8-Trichloro-1,7-diazanaphthalene
EINECS	Contact for details

Quality Control

Our 3,4,8-Trichloro-1,7-Naphthyridine is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) are provided with each shipment, detailing all critical quality attributes. We support cGMP and ISO compliant production for advanced applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Keep away from incompatible materials such as strong bases and reducing agents. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.