Description

5-(4-Fluoro-Phenyl)-Pent-2-Enoic Acid Methyl Ester is a high-purity fluorinated organic intermediate, specifically a methyl ester derivative of an unsaturated carboxylic acid. This compound is valued for its versatile chemical reactivity, particularly as a key building block in the synthesis of complex pharmaceutical molecules and advanced agrochemicals. It is primarily sought by R&D chemists and process development teams in the pharmaceutical, agrochemical, and specialty chemical industries for constructing novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of active pharmaceutical ingredients (APIs), especially those containing fluorinated aromatic systems for enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, where the fluorophenyl moiety can improve pesticidal activity and environmental profile.
• Liquid Crystal & OLED Material Research: Serves as a building block for fluorinated organic electronic materials due to its conjugated system and fluorine atom, which can influence charge transport and optical properties.
• Chemical Biology & Probe Development: Utilized in medicinal chemistry for creating molecular probes and tool compounds to study biological targets and pathways.
• Custom Synthesis & Contract Manufacturing: Employed by CDMOs (Contract Development and Manufacturing Organizations) for bespoke synthesis projects requiring specific fluorinated intermediates.
• Academic & Industrial R&D: A valuable reagent for methodological development in organic synthesis, including cross-coupling reactions and functional group transformations.

Basic Information

Product Name	5-(4-Fluoro-Phenyl)-Pent-2-Enoic Acid Methyl Ester
CAS No.	1313714-60-1
Molecular Formula	C₁₂H₁₃FO₂
Molecular Weight	208.23 g/mol
Synonyms	Methyl 5-(4-fluorophenyl)pent-2-enoate; (E)-Methyl 5-(4-fluorophenyl)pent-2-enoate; Methyl (E)-5-(4-Fluorophenyl)-2-pentenoate; 5-(4-Fluorophenyl)-2-pentenoic Acid Methyl Ester; 2-Pentenoic acid, 5-(4-fluorophenyl)-, methyl ester; 1313714-60-1; 5-(p-Fluorophenyl)pent-2-enoic acid methyl ester
EINECS	Contact for details

Quality Control

Our 5-(4-Fluoro-Phenyl)-Pent-2-Enoic Acid Methyl Ester is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide Certificates of Analysis (COA) with detailed specifications for every shipment, supporting your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). The compound may be sensitive to prolonged exposure to heat and moisture. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Area %)
Isomeric Purity (GC/HPLC)	≥ 95.0% (E-isomer)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.