Description

3-(2-Trimethylsilanyl-Ethoxymethyl)-6-Vinyl-3H-[1,2,3]Triazolo[4,5-B]Pyridine is a specialized heterocyclic building block designed for advanced organic synthesis. This compound matters because it provides a unique molecular scaffold combining a triazolopyridine core with vinyl and silyl-protected functional handles, enabling precise chemical modifications. It is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for constructing complex molecules, particularly in medicinal chemistry programs and material science research.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates, especially those targeting kinase inhibition or other biological pathways where the triazolopyridine moiety is pharmacologically active.
• Agrochemical Research: Used in the development of new herbicides, fungicides, or insecticides, leveraging its heterocyclic structure for bioactivity.
• Material Science: Acts as a functional monomer or cross-linking agent in the creation of advanced polymers and specialty materials due to its reactive vinyl group.
• Chemical Biology: Employed in the design and synthesis of molecular probes, tags, or linkers for studying biological systems.
• Organic Synthesis Building Block: Provides a versatile platform for further derivatization via the vinyl group (e.g., polymerization, cross-coupling) and the silyl-protected alcohol (after deprotection).
• Ligand Synthesis: Utilized in the preparation of complex ligands for catalysis or metal-organic frameworks (MOFs).

Basic Information

Product Name	3-(2-Trimethylsilanyl-Ethoxymethyl)-6-Vinyl-3H-[1,2,3]Triazolo[4,5-B]Pyridine
CAS No.	1313712-65-0
Molecular Formula	C14H24N4OSi
Molecular Weight	292.45 g/mol
Synonyms	6-Vinyl-3-((2-(trimethylsilyl)ethoxy)methyl)-3H-[1,2,3]triazolo[4,5-b]pyridine; 3-((2-(Trimethylsilyl)ethoxy)methyl)-6-vinyl-[1,2,3]triazolo[4,5-b]pyridine; 6-Ethenyl-3-[(2-trimethylsilylethoxy)methyl][1,2,3]triazolo[4,5-b]pyridine; 3-(2-Trimethylsilylethoxymethyl)-6-vinyl-3H-[1,2,3]triazolo[4,5-b]pyridine; 6-Vinyl-3H-[1,2,3]triazolo[4,5-b]pyridine, 3-[(2-(trimethylsilyl)ethoxy)methyl]-; SEM-protected 6-vinyltriazolopyridine; VTTP-SEM
EINECS	Contact for details

Quality Control

Our 3-(2-Trimethylsilanyl-Ethoxymethyl)-6-Vinyl-3H-[1,2,3]Triazolo[4,5-B]Pyridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We support cGMP compliance for pharmaceutical applications and can tailor purity grades to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This compound is moisture-sensitive (hygroscopic) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95% (Standard Grade)
Purity (HPLC)	≥ 98% (High Purity Grade)
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.