Description

1-tert-Butyl 4-Ethyl 2-Oxopiperidine-1,4-Dicarboxylate is a high-purity, protected piperidine derivative serving as a critical synthetic intermediate. Its value lies in providing a versatile and reactive scaffold for constructing complex nitrogen-containing molecules, enabling precise control over molecular architecture. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for the synthesis of novel active pharmaceutical ingredients (APIs) and advanced crop protection agents.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of piperidine-based drug candidates, including potential central nervous system (CNS) agents and enzyme inhibitors.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides that require complex heterocyclic cores.
• Organic Synthesis Research: A versatile reagent for academic and industrial R&D focused on heterocyclic chemistry, methodology development, and library synthesis.
• Peptidomimetics & Bioactive Molecule Construction: Employed to introduce constrained, functionalized piperidine motifs that mimic peptide structures for drug discovery.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of bespoke intermediates under cGMP conditions.

Basic Information

Product Name	1-tert-Butyl 4-Ethyl 2-Oxopiperidine-1,4-Dicarboxylate
CAS No.	1313498-26-8
Molecular Formula	C13H21NO5
Molecular Weight	271.31 g/mol
Synonyms	1-tert-Butoxycarbonyl-4-ethoxycarbonyl-2-piperidinone; 4-Ethyl 1-(tert-butyl) 2-oxopiperidine-1,4-dicarboxylate; tert-Butyl 4-(ethoxycarbonyl)-2-oxo-1-piperidinecarboxylate; 1-Boc-4-(COOEt)-2-piperidinone; 2-Oxo-1,4-piperidinedicarboxylic acid 1-tert-butyl 4-ethyl ester; 1-(tert-Butoxycarbonyl)-4-(ethoxycarbonyl)-2-piperidinone; N-Boc-4-(ethoxycarbonyl)-2-piperidinone
EINECS	Contact for details

Quality Control

Our 1-tert-Butyl 4-Ethyl 2-Oxopiperidine-1,4-Dicarboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. For advanced applications, we can supply material produced under controlled environments suitable for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); the container must be kept tightly sealed in a dry environment to prevent degradation. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.