Description

1H-Pyrrolo[2,3-B]Pyridine-3-Carboxylic Acid, 2-(Bromomethyl)-5-Chloro-1-(Phenylsulfonyl)-, Methyl Ester is a high-value, multi-functional heterocyclic building block designed for advanced synthetic chemistry. This compound is engineered to serve as a critical intermediate in the development of complex active pharmaceutical ingredients (APIs) and other fine chemicals. It is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and material science industries for constructing novel molecular architectures.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of kinase inhibitors and other small-molecule drug candidates targeting various therapeutic areas.
• Agrochemical Research: Used in the development of novel pesticides and herbicides, leveraging its halogenated and sulfonylated structure for bioactivity.
• Chemical Biology: Serves as a versatile scaffold for creating molecular probes and tool compounds to study biological pathways.
• Material Science Precursor: Potential building block for organic electronic materials and specialty polymers due to its fused heterocyclic core.
• Custom Synthesis & Contract Manufacturing: Employed by CDMOs for the custom production of complex molecules for client R&D and scale-up projects.

Basic Information

Product Name	1H-Pyrrolo[2,3-B]Pyridine-3-Carboxylic Acid, 2-(Bromomethyl)-5-Chloro-1-(Phenylsulfonyl)-, Methyl Ester
CAS No.	1312755-56-8
Molecular Formula	C16H14BrClN2O4S
Molecular Weight	445.72 g/mol
Synonyms	Methyl 2-(bromomethyl)-5-chloro-1-(phenylsulfonyl)-1H-pyrrolo[2,3-b]pyridine-3-carboxylate; 1H-Pyrrolo[2,3-b]pyridine-3-carboxylic acid, 2-(bromomethyl)-5-chloro-1-(phenylsulfonyl)-, methyl ester; 2-(Bromomethyl)-5-chloro-1-tosyl-1H-pyrrolo[2,3-b]pyridine-3-carboxylic acid methyl ester; 1312755-56-8; 5-Chloro-2-(bromomethyl)-1-(phenylsulfonyl)-1H-pyrrolo[2,3-b]pyridine-3-carboxylic acid methyl ester
EINECS	Contact for details

Quality Control

Our 1H-Pyrrolo[2,3-B]Pyridine-3-Carboxylic Acid, 2-(Bromomethyl)-5-Chloro-1-(Phenylsulfonyl)-, Methyl Ester is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific client or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.