Description

2-Pyridinamine, 5-Bromo-3-(1-Propyn-1-Yl)- is a specialized brominated pyridine derivative featuring a propynyl substituent, serving as a high-value synthetic intermediate. This compound is critical for constructing complex molecular architectures in advanced research and development. It is primarily sought after by pharmaceutical, agrochemical, and material science industries for applications in medicinal chemistry, ligand synthesis, and the development of functional organic materials.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other targeted therapies.
• Agrochemical Research: Used in the development of new generation herbicides, fungicides, and plant growth regulators.
• Material Science Precursor: Serves as a monomer or functional unit in the creation of organic semiconductors, liquid crystals, and metal-organic frameworks (MOFs).
• Ligand Synthesis: Employed in the preparation of specialized ligands for catalysis and coordination chemistry.
• Chemical Biology Probes: Utilized to create molecular probes for studying biological pathways and protein functions.
• Cross-Coupling Reactions: Acts as a substrate in Suzuki, Sonogashira, and other palladium-catalyzed cross-coupling reactions to form complex biaryl systems.

Basic Information

Product Name	2-Pyridinamine, 5-Bromo-3-(1-Propyn-1-Yl)-
CAS No.	1312755-43-3
Molecular Formula	C8H7BrN2
Molecular Weight	211.06 g/mol
Synonyms	5-Bromo-3-(prop-1-yn-1-yl)pyridin-2-amine; 5-Bromo-3-prop-1-yn-1-ylpyridin-2-amine; 2-Amino-5-bromo-3-prop-1-ynylpyridine; 3-Propynyl-5-bromo-2-pyridinamine; 5-Bromo-3-propynyl-2-aminopyridine; 5-Bromo-3-(1-propynyl)-2-pyridinamine
EINECS	Contact for details

Quality Control

Our 2-Pyridinamine, 5-Bromo-3-(1-Propyn-1-Yl)- is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with customer specifications and relevant industry standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.