Description

4,6-Dichloro-7-Fluoro-1-Hydroxy-1H-Pyrrolo[3,4-C]Pyridin-3(2H)-One is a high-purity, advanced pharmaceutical intermediate of significant commercial interest. Its complex heterocyclic structure, featuring halogen substituents, makes it a critical building block in modern medicinal chemistry. This compound is primarily sought after by research institutions and pharmaceutical manufacturers for the development of novel active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, particularly in oncology and antiviral research.
• Active Pharmaceutical Ingredient (API) Development: Serves as a core scaffold for constructing new molecular entities with targeted biological activity.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to optimize potency and selectivity of lead compounds.
• Process Chemistry & Scale-Up: Employed in route scouting and optimization for efficient, large-scale API manufacturing.
• Contract Research & Manufacturing (CRO/CMO): Supplied to service organizations supporting drug discovery and development pipelines.
• Reference Standard: Utilized as an analytical standard for quality control and regulatory submissions.

Basic Information

Product Name	4,6-Dichloro-7-Fluoro-1-Hydroxy-1H-Pyrrolo[3,4-C]Pyridin-3(2H)-One
CAS No.	1312693-68-7
Molecular Formula	C7H3Cl2FNO2
Molecular Weight	237.01 g/mol
Synonyms	4,6-Dichloro-7-fluoro-1-hydroxy-2,3-dihydro-1H-pyrrolo[3,4-c]pyridin-3-one; 1H-Pyrrolo[3,4-c]pyridin-3(2H)-one, 4,6-dichloro-7-fluoro-1-hydroxy-; 1312693-68-7; 4,6-Dichloro-7-fluoro-1-hydroxy-1,2-dihydropyrrolo[3,4-c]pyridin-3-one; 7-Fluoro-4,6-dichloro-1-hydroxy-1H-pyrrolo[3,4-c]pyridin-3(2H)-one
EINECS	Contact for details

Quality Control

Our 4,6-Dichloro-7-Fluoro-1-Hydroxy-1H-Pyrrolo[3,4-C]Pyridin-3(2H)-One is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The container should be kept tightly sealed in a dry environment to minimize exposure to moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.