Description

5-Chloro-2-Hydroxy-4-Iodo-Benzoic Acid Methyl Ester is a high-purity, multi-functional halogenated aromatic building block of significant interest in advanced organic synthesis. Its unique substitution pattern makes it a valuable precursor for constructing complex molecules, particularly in pharmaceutical and agrochemical research. This compound is primarily sought by R&D chemists and process development scientists working on active pharmaceutical ingredients (APIs), specialty agrochemicals, and advanced material science applications.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, especially in antimicrobial and anti-inflammatory research.
• Agrochemical Synthesis: Used in the development of advanced herbicides and fungicides, leveraging its halogenated aromatic structure.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in transition metal catalysis.
• Material Science Research: Employed in the synthesis of organic electronic materials and liquid crystals.
• Chemical Biology Probes: Useful for synthesizing tagged molecules for studying biological pathways and mechanisms.
• Custom Synthesis and Contract Manufacturing: A critical starting material for custom synthesis projects requiring specific halogenated benzoic acid derivatives.

Basic Information

Product Name	5-Chloro-2-Hydroxy-4-Iodo-Benzoic Acid Methyl Ester
CAS No.	1312685-16-7
Molecular Formula	C8H6ClIO3
Molecular Weight	312.49 g/mol
Synonyms	Methyl 5-Chloro-2-hydroxy-4-iodobenzoate; 5-Chloro-4-iodo-2-hydroxybenzoic Acid Methyl Ester; Benzoic acid, 5-chloro-2-hydroxy-4-iodo-, methyl ester; 2-Hydroxy-5-chloro-4-iodobenzoic Acid Methyl Ester; Methyl 5-Chloro-4-iodosalicylate; 5-Chloro-4-iodosalicylic Acid Methyl Ester
EINECS	Contact for details

Quality Control

Our 5-Chloro-2-Hydroxy-4-Iodo-Benzoic Acid Methyl Ester is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity for research and development applications. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing key parameters such as identity, assay, and impurity profiles. Our quality systems are designed to support customers requiring material for GLP or early-stage GMP synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.