Description

1,4-Dioxa-7-Azaspiro[4.5]Decan-8-One is a high-purity spirocyclic building block of significant interest in advanced organic synthesis. Its unique heterocyclic structure makes it a valuable intermediate for constructing complex molecular architectures with precise stereochemistry. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for applications in medicinal chemistry and crop protection science.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and antiviral drug discovery programs.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where its spirocyclic core contributes to biological activity and metabolic stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the synthesis of specialty polymers and organic frameworks with tailored properties.
• Chemical Biology Probes: Utilized as a scaffold for developing molecular probes to study enzyme function and biological pathways.
• Academic & Industrial R&D: A versatile building block for method development and exploratory synthesis in contract research organizations (CROs) and university laboratories.

Basic Information

Product Name	1,4-Dioxa-7-Azaspiro[4.5]Decan-8-One
CAS No.	1312457-11-6
Molecular Formula	C8H13NO3
Molecular Weight	171.19 g/mol
Synonyms	8-Oxo-1,4-dioxa-7-azaspiro[4.5]decane; 7-Aza-1,4-dioxaspiro[4.5]decan-8-one; 1,4-Dioxa-7-azaspiro[4.5]decan-8-one; Spirocyclic lactam ether; Tetrahydro-2H,5H-[1,3]dioxolo[4,5-c]pyridin-6(7H)-one
EINECS	Contact for details

Quality Control

Our 1,4-Dioxa-7-Azaspiro[4.5]Decan-8-One is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and scale-up. We provide comprehensive analytical data, including HPLC/GC purity, NMR, and mass spectrometry confirmation. Certificates of Analysis (COA) are available for every batch upon request, detailing all relevant specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.