Description

2-Bromo-5-Chloro-3-Fluoropyridin-4-Ol is a high-purity, multi-halogenated pyridine derivative serving as a critical building block in advanced organic synthesis. This compound is valued for its unique substitution pattern, which enables precise molecular modifications in complex chemical architectures. It is primarily sought after by R&D and process chemistry teams in the pharmaceutical and agrochemical industries for the development of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key synthon for the research and development of new drug candidates, particularly in kinase inhibitor and antiviral therapeutic areas.
• Agrochemical Synthesis: Used in the creation of advanced herbicides, fungicides, and insecticides, leveraging its halogenated structure for bioactivity.
• Material Science Research: Serves as a precursor for functionalized ligands and monomers in the development of specialty polymers and electronic materials.
• Chemical Biology: Employed as a probe or labeling agent in biochemical research due to its reactive halogen sites.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis projects requiring specific, complex halogenated pyridine cores.

Basic Information

Product Name	2-Bromo-5-Chloro-3-Fluoropyridin-4-Ol
CAS No.	1312440-86-0
Molecular Formula	C5H2BrClFNO
Molecular Weight	226.43 g/mol
Synonyms	4-Hydroxy-2-bromo-5-chloro-3-fluoropyridine; 2-Bromo-5-chloro-3-fluoro-4-hydroxypyridine; 2-Bromo-5-chloro-3-fluoro-4-pyridinol; 1312440-86-0; 4-Pyridinol, 2-bromo-5-chloro-3-fluoro-
EINECS	Contact for details

Quality Control

Our 2-Bromo-5-Chloro-3-Fluoropyridin-4-Ol is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. A Certificate of Analysis (COA) detailing all specifications is provided with each shipment to ensure traceability and compliance with your project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.