Description

Mes-Peg2-Acid T-Butyl Ester is a specialized bifunctional PEG linker featuring a mesylate leaving group and a protected carboxylic acid. This compound is engineered to facilitate controlled bioconjugation and the synthesis of complex molecular architectures. It serves as a critical building block for researchers and manufacturers in the pharmaceutical and biotechnology sectors, enabling the development of advanced drug delivery systems, diagnostic agents, and novel biomaterials.

Application

• Bioconjugation Reagent: Used for the controlled attachment of drugs, peptides, or fluorescent dyes to antibodies, proteins, or nanoparticles.
• ADC (Antibody-Drug Conjugate) Development: A key intermediate in the synthesis of linkers for constructing stable and efficacious ADCs.
• Polymer Chemistry: Serves as a functional monomer or chain transfer agent for synthesizing tailored, functionalized polyethylene glycol (PEG) polymers.
• Proteomics Research: Employed in the modification of biomolecules for studying protein interactions, stability, and function.
• Diagnostic Agent Synthesis: Facilitates the creation of contrast agents and molecular probes for imaging applications.
• Cross-linking Agent: Used to create hydrogels or cross-linked polymer networks with specific degradation profiles.

Basic Information

Product Name	Mes-Peg2-Acid T-Butyl Ester
CAS No.	1312309-62-8
Molecular Formula	C14H28O7S
Molecular Weight	340.43 g/mol
Synonyms	2-[2-(2-Methoxyethoxy)ethoxy]ethyl methanesulfonate tert-butyl ester; tert-Butyl 2-[2-(2-methoxyethoxy)ethoxy]ethyl methanesulfonate; PEG2 Mesylate t-Butyl Ester; Methanesulfonic acid 2-[2-(2-methoxyethoxy)ethoxy]ethyl ester, 1,1-dimethylethyl ester; Mes-PEG2-t-butyl ester; 1-tert-Butyl 2-[2-(2-methoxyethoxy)ethyl] methanedisulfonate; Bifunctional PEG linker, Mesylate-Acid tBu ester
EINECS	Contact for details

Quality Control

Our Mes-Peg2-Acid T-Butyl Ester is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR for structural confirmation, and MS for identity verification, to ensure it meets the high standards required for research and pharmaceutical applications. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as indicated on the label or COA. The product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere for long-term storage to maintain stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.