Description

Boronic Acid, B-[4-[[4-[(Z)-[3-[(4-Fluorophenyl)Methyl]-2,4-Dioxo-5-Thiazolidinylidene]Methyl]Phenoxy]Methyl]Phenyl]- is a sophisticated, high-purity organic building block designed for advanced synthetic chemistry. This compound is critical for researchers and manufacturers developing novel active pharmaceutical ingredients (APIs) and functional materials. It is primarily utilized by pharmaceutical R&D teams, agrochemical innovators, and specialty chemical producers who require precise molecular scaffolds for Suzuki-Miyaura cross-coupling reactions and other palladium-catalyzed transformations.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, particularly those targeting metabolic and inflammatory pathways.
• Agrochemical Research: Used in the development of new herbicides and fungicides with enhanced efficacy and selectivity.
• Material Science: Serves as a monomer or cross-linking agent in the creation of advanced polymers and organic electronic materials.
• Chemical Biology Probes: Employed in the design of activity-based probes and sensors for studying biological processes.
• Catalyst Ligand Development: Acts as a starting material for synthesizing novel ligands used in homogeneous catalysis.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs for the production of bespoke compounds under cGMP conditions.

Basic Information

Product Name	Boronic Acid, B-[4-[[4-[(Z)-[3-[(4-Fluorophenyl)Methyl]-2,4-Dioxo-5-Thiazolidinylidene]Methyl]Phenoxy]Methyl]Phenyl]-
CAS No.	1312201-00-5
Molecular Formula	C26H21BFNO4S
Molecular Weight	473.33 g/mol
Synonyms	4-[[4-[(Z)-[3-[(4-Fluorophenyl)methyl]-2,4-dioxo-5-thiazolidinylidene]methyl]phenoxy]methyl]benzeneboronic acid; (4-((4-((Z)-(3-((4-Fluorobenzyl)thiazolidine-2,4-dione-5-ylidene)methyl)phenoxy)methyl)phenyl)boronic acid; B-[4-[[4-[(Z)-[3-[(4-Fluorophenyl)Methyl]-2,4-Dioxo-5-Thiazolidinylidene]Methyl]Phenoxy]Methyl]Phenyl]Boronic Acid; CAS 1312201-00-5; Thiazolidinedione-based boronic acid; Fluorophenyl-thiazolidinedione boronate ester precursor.
EINECS	Contact for details

Quality Control

Our Boronic Acid, B-[4-[[4-[(Z)-[3-[(4-Fluorophenyl)Methyl]-2,4-Dioxo-5-Thiazolidinylidene]Methyl]Phenoxy]Methyl]Phenyl]- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR for structural confirmation, and Karl Fischer titration for moisture content, to ensure compliance with research and pharmaceutical-grade standards. Comprehensive Certificates of Analysis (COA) with full traceability are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.