Description

1-[3-Chloro-5-(Trifluoromethyl)Pyridin-2-Yl]-Azetidin-3-Ol is a high-value pharmaceutical intermediate and building block characterized by its unique heterocyclic structure. This compound is critical for the synthesis of advanced active pharmaceutical ingredients (APIs) and agrochemicals, offering a versatile scaffold for further functionalization. It is primarily utilized by research and development teams in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop novel compounds with targeted biological activity.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly in central nervous system (CNS) and anti-infective therapeutic areas.
• Agrochemical Synthesis: Used in the research and development of next-generation pesticides and herbicides, leveraging the pyridine and azetidine motifs for bioactivity.
• Chemical Research & Development: Serves as a versatile scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and library synthesis.
• Ligand and Catalyst Precursor: Potential use in the development of specialized ligands for catalysis or metal-organic frameworks (MOFs).

Basic Information

Product Name	1-[3-Chloro-5-(Trifluoromethyl)Pyridin-2-Yl]-Azetidin-3-Ol
CAS No.	1311798-09-0
Molecular Formula	C9H6ClF3N2O
Molecular Weight	250.60 g/mol
Synonyms	1-[3-Chloro-5-(trifluoromethyl)-2-pyridinyl]-3-azetidinol; 3-Azetidinol, 1-[3-chloro-5-(trifluoromethyl)-2-pyridinyl]-; 1-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)azetidin-3-ol; Azetidin-3-ol, 1-[3-chloro-5-(trifluoromethyl)-2-pyridinyl]-; 1311798-09-0; 1-(3-Chloro-5-trifluoromethylpyridin-2-yl)azetidin-3-ol
EINECS	Contact for details

Quality Control

Our 1-[3-Chloro-5-(Trifluoromethyl)Pyridin-2-Yl]-Azetidin-3-Ol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical and agrochemical R&D. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.