Description

[1,1'-Biphenyl]-4-Carboxylic Acid, 3'-(Bromomethyl)-, Methyl Ester is a high-purity, functionalized biphenyl derivative designed for advanced organic synthesis. This compound serves as a critical building block in the development of complex molecules, offering a reactive bromomethyl handle for further functionalization. It is primarily utilized by researchers and process chemists in the pharmaceutical and agrochemical industries for the synthesis of active ingredients and novel materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the research and production of advanced crop protection agents and herbicides.
• Ligand and Catalyst Development: Serves as a precursor for creating sophisticated ligands used in catalytic systems and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of organic semiconductors, liquid crystals, and polymers with specific electronic or structural properties.
• Cross-Coupling Reactions: The biphenyl core and bromomethyl group make it a suitable substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions.
• Chemical Biology Probes: Useful for creating tagged molecules or probes for studying biological pathways and target engagement.

Basic Information

Product Name	[1,1'-Biphenyl]-4-Carboxylic Acid, 3'-(Bromomethyl)-, Methyl Ester
CAS No.	1311291-88-9
Molecular Formula	C16H15BrO2
Molecular Weight	319.20 g/mol
Synonyms	3'-(Bromomethyl)-[1,1'-biphenyl]-4-carboxylic acid methyl ester; Methyl 3'-(bromomethyl)biphenyl-4-carboxylate; 4'-(Methoxycarbonyl)-[1,1'-biphenyl]-3-ylmethyl bromide; Biphenyl-4-carboxylic acid, 3'-(bromomethyl)-, methyl ester; [1,1'-Biphenyl]-4-carboxylic acid, 3'-(bromomethyl)-, methyl ester (9CI)
EINECS	Contact for details

Quality Control

Our [1,1'-Biphenyl]-4-Carboxylic Acid, 3'-(Bromomethyl)-, Methyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and process chemistry. Certificates of Analysis (COA) detailing all specifications are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong bases and incompatible organic solvents. The compound is light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.