Description

1-[4-(6-Dimethylamino-4-Trifluoromethyl-Pyridin-2-Yl)-Phenyl]-Ethanone is a high-value, structurally advanced organic intermediate featuring a trifluoromethylpyridine core, which is critical for imparting unique physicochemical properties to final compounds. This compound matters because it serves as a versatile building block for the synthesis of sophisticated active pharmaceutical ingredients (APIs) and agrochemicals, where the trifluoromethyl group enhances metabolic stability, lipophilicity, and bioavailability. Industrial and pharmaceutical R&D teams require this precise chemical scaffold to develop new generations of fluorinated drugs and crop protection agents with improved efficacy and patent life.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel, fluorinated active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) drugs, antiviral agents, and anti-inflammatory medications.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the trifluoromethyl group contributes to enhanced biological activity and environmental persistence.
• Material Science Research: Serves as a monomer or functional additive in the development of specialty polymers, liquid crystals, and organic electronic materials due to its electron-withdrawing characteristics.
• Chemical Biology & Proteomics: Employed as a chemical probe or labeling agent in biochemical research to study protein-ligand interactions and enzyme mechanisms.
• Dye & Pigment Industry: Acts as an intermediate for creating high-performance, light-fast fluorinated dyes and organic pigments.

Basic Information

Product Name	1-[4-(6-Dimethylamino-4-Trifluoromethyl-Pyridin-2-Yl)-Phenyl]-Ethanone
CAS No.	1311280-01-9
Molecular Formula	C₁₆H₁₅F₃N₂O
Molecular Weight	308.30 g/mol
Synonyms	2-Acetyl-4'-(6-(dimethylamino)-4-(trifluoromethyl)pyridin-2-yl)acetophenone; 1-[4-[6-(Dimethylamino)-4-(trifluoromethyl)-2-pyridinyl]phenyl]ethanone; 2-Acetyl-4'-(6-dimethylamino-4-trifluoromethyl-2-pyridinyl)acetophenone; 4'-(6-Dimethylamino-4-trifluoromethyl-pyridin-2-yl)acetophenone; 2-Acetyl-4'-(6-(N,N-dimethylamino)-4-(trifluoromethyl)pyridin-2-yl)acetophenone; Ethanone, 1-[4-[6-(dimethylamino)-4-(trifluoromethyl)-2-pyridinyl]phenyl]-; CAS 1311280-01-9
EINECS	Contact for details

Quality Control

Our 1-[4-(6-Dimethylamino-4-Trifluoromethyl-Pyridin-2-Yl)-Phenyl]-Ethanone is manufactured under a strict quality management system to ensure batch-to-batch consistency and high purity suitable for sensitive synthetic applications. Each lot undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to verify identity and purity against established reference standards. Certificates of Analysis (COA) detailing all test results are provided and can be tailored to meet specific customer or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents and bases. For long-term storage, consider under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.