Description

4-(3-Chloro-5-Trifluoromethyl-Pyridin-2-Ylmethyl)-Piperazine-1-Carbothioic Acid (4-Chloro-Phen CAS NO 1311278-34-8 is a high-value, multifunctional heterocyclic building block featuring a piperazine-thioamide core linked to a chlorinated trifluoromethyl pyridine moiety. This compound is engineered to serve as a critical intermediate in advanced organic synthesis, offering significant versatility for constructing complex molecular architectures. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical sectors for the creation of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of potential drug candidates, particularly for central nervous system (CNS) and anti-infective agents.
• Agrochemical Synthesis: Building block for developing new-generation herbicides, fungicides, and insecticides leveraging its halogenated pyridine structure.
• Chemical Research & Development: Used in medicinal chemistry for structure-activity relationship (SAR) studies and library synthesis.
• Ligand & Catalyst Development: The piperazine-thioamide group can act as a chelating agent or ligand in metal-catalyzed reactions.
• Material Science Precursor: Potential intermediate for synthesizing specialty polymers or functional materials with specific electronic properties.

Basic Information

Product Name	4-(3-Chloro-5-Trifluoromethyl-Pyridin-2-Ylmethyl)-Piperazine-1-Carbothioic Acid (4-Chloro-Phen CAS NO 1311278-34-8
CAS No.	1311278-34-8
Molecular Formula	C12H11ClF3N3OS
Molecular Weight	337.75 g/mol
Synonyms	4-[(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)methyl]piperazine-1-carbothioic acid; 4-Chloro-Phen; 4-(3-Chloro-5-trifluoromethyl-pyridin-2-ylmethyl)-piperazine-1-carbothioic acid; 1-Piperazinecarbothioic acid, 4-[[3-chloro-5-(trifluoromethyl)-2-pyridinyl]methyl]-; 1311278-34-8; 4-(3-Chloro-5-trifluoromethyl-2-pyridylmethyl)piperazine-1-carbothioic acid; 4-((3-Chloro-5-(trifluoromethyl)pyridin-2-yl)methyl)piperazine-1-carbothioic acid
EINECS	Contact for details

Quality Control

Our production of 4-(3-Chloro-5-Trifluoromethyl-Pyridin-2-Ylmethyl)-Piperazine-1-Carbothioic Acid adheres to stringent quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets precise customer specifications. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This compound may be moisture-sensitive; keep the container tightly sealed under an inert atmosphere if specified. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.