Description

(R)-1-(4-Pyridinyl)Propylamine 2Hcl is a high-purity chiral amine derivative, specifically the dihydrochloride salt of the (R)-enantiomer. This compound serves as a critical chiral building block and intermediate in advanced pharmaceutical synthesis, enabling the development of enantiomerically pure active pharmaceutical ingredients (APIs). It is essential for research and production in pharmaceutical chemistry, agrochemical development, and fine chemical manufacturing where stereochemical control is paramount.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the research and development of novel therapeutic agents, particularly in central nervous system (CNS) and antiviral drug candidates.
• Asymmetric Synthesis: Used as a chiral auxiliary or resolving agent in stereoselective chemical reactions to produce single-enantiomer compounds.
• Agrochemical Research: Intermediate in the synthesis of chiral pesticides and herbicides, where specific stereochemistry can influence biological activity and environmental safety.
• Ligand and Catalyst Development: Building block for creating chiral ligands used in transition metal catalysis for asymmetric hydrogenation and other key transformations.
• Fine Chemical Production: Precursor in the manufacture of specialty chemicals, flavors, and fragrances requiring high enantiomeric purity.
• Academic and R&D Laboratories: Reference standard and starting material for methodological studies in organic and medicinal chemistry.

Basic Information

Product Name	(R)-1-(4-Pyridinyl)Propylamine 2Hcl
CAS No.	1311254-88-2
Molecular Formula	C8H14N2 • 2HCl
Molecular Weight	223.13 g/mol (Free base: 150.22 g/mol)
Synonyms	(R)-1-(4-Pyridyl)propylamine dihydrochloride; (R)-1-(Pyridin-4-yl)propan-1-amine dihydrochloride; (R)-γ-(4-Pyridyl)propylamine hydrochloride; (R)-4-(1-Aminopropyl)pyridine dihydrochloride; (R)-Norsertraline impurity; (R)-Enantiomer of 1-(4-Pyridinyl)propylamine 2HCl
EINECS	Contact for details

Quality Control

Our (R)-1-(4-Pyridinyl)Propylamine 2Hcl is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the stringent requirements for pharmaceutical R&D. A detailed Certificate of Analysis (COA) providing purity, enantiomeric excess (ee), and impurity profile is supplied with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.