Description

4-Nitrophenoxycarbonyl 2,3,4-Tri-o-Benzyl-β-D-Glucopyranuronic Acid Benzyl Ester is a sophisticated, protected glucuronic acid derivative that serves as a critical synthetic intermediate. Its value lies in enabling the controlled synthesis and modification of complex carbohydrate structures, which are essential for advanced research and development. This compound is primarily needed by pharmaceutical researchers and fine chemical manufacturers working on glycosylation reactions, prodrug development, and the synthesis of bioactive glycoconjugates.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel glycosylated drug candidates and prodrugs.
• Glycoconjugate Synthesis: Used in the preparation of complex oligosaccharides, glycopeptides, and glycolipids for biological studies.
• Carbohydrate Chemistry Research: Essential reagent for developing new glycosylation methodologies and protecting group strategies.
• Bioconjugation: Acts as an activated ester for coupling sugars to proteins, peptides, or other biomolecules.
• Diagnostic Reagent Development: Potential use in creating enzyme substrates or probes for glycosidase activity assays.
• Material Science: Intermediate for synthesizing specialty polymers or surfaces with carbohydrate functionalities.

Basic Information

Product Name	4-Nitrophenoxycarbonyl 2,3,4-Tri-o-Benzyl-β-D-Glucopyranuronic Acid Benzyl Ester
CAS No.	1311144-66-7
Molecular Formula	C₃₄H₃₁NO₁₀
Molecular Weight	613.61 g/mol
Synonyms	Benzyl 2,3,4-Tri-O-benzyl-α/β-D-glucopyranosiduronic Acid 1-(4-Nitrophenyl) Ester; PNP 2,3,4-Tri-O-benzyl-D-glucopyranuronate; 4-Nitrophenyl 2,3,4-Tri-O-benzyl-1-O-(benzyl D-glucopyranosid)uronate; Glucuronic Acid, Benzyl Ester, 2,3,4-Tri-O-benzyl-, 1-(4-Nitrophenyl) Ester; Protected Glucuronic Acid PNP Ester; Activated Benzyl-Protected Glucuronate
EINECS	Contact for details

Quality Control

Our 4-Nitrophenoxycarbonyl 2,3,4-Tri-o-Benzyl-β-D-Glucopyranuronic Acid Benzyl Ester is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by NMR and mass spectrometry, to ensure it meets the exacting standards required for synthetic chemistry. Certificates of Analysis (COA) with full characterization data are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as indicated on the label. This compound is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability. Allow the sealed container to equilibrate to room temperature before opening to prevent moisture condensation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.