Description

6-Iodo-2-Methoxypyridin-3-Amine is a high-purity halogenated pyridine derivative, serving as a critical building block in advanced organic synthesis. Its unique structure, featuring both an iodine substituent and an amine group, makes it a versatile intermediate for constructing complex molecules. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for applications in medicinal chemistry and material science.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the development of novel pesticides and herbicides, leveraging its halogenated pyridine core.
• Material Science Research: Serves as a monomer or functionalizing agent in the creation of specialty polymers and organic electronic materials.
• Cross-Coupling Reactions: The iodine atom makes it an excellent substrate for palladium-catalyzed reactions like Suzuki, Sonogashira, and Buchwald-Hartwig amination.
• Chemical Biology: Utilized as a probe or linker in bioconjugation and the development of molecular imaging agents.
• Academic & Contract Research: Essential for method development and exploratory synthesis in university and CRO laboratories.

Basic Information

Item	Detail
Product Name	6-Iodo-2-Methoxypyridin-3-Amine
CAS No.	1310949-50-8
Molecular Formula	C6H7IN2O
Molecular Weight	250.04 g/mol
Synonyms	3-Amino-6-iodo-2-methoxypyridine; 2-Methoxy-6-iodopyridin-3-amine; 6-Iodo-2-methoxy-3-pyridinamine; 6-Iodo-2-methoxypyridin-3-ylamine; 1310949-50-8
EINECS	Contact for details

Quality Control

Every batch of 6-Iodo-2-Methoxypyridin-3-Amine is manufactured under strict quality management systems. We employ advanced analytical techniques including HPLC, GC, NMR, and mass spectrometry to verify identity, purity, and consistency. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) with detailed chromatographic data are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (HPLC/IR)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Single Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.