Description

tert-Butyl 2-Phenyl-6,7-dihydro-2H-pyrazolo[4,3-c]pyridine-5(4H)-carboxylate is a high-purity, advanced pharmaceutical intermediate of significant commercial and research interest. This compound serves as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly those targeting central nervous system and oncological pathways. It is essential for medicinal chemistry research, process development, and scale-up manufacturing within the global pharmaceutical and biotechnology sectors.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, especially kinase inhibitors and other small molecule therapeutics.
• Medicinal Chemistry Research: Used in hit-to-lead optimization and structure-activity relationship (SAR) studies for new drug discovery programs.
• Process Chemistry & Scale-Up: Employed in route scouting, process development, and cGMP manufacturing for clinical trial material.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and development services.
• Academic Research: Utilized in university and institutional labs for studying heterocyclic chemistry and developing new synthetic methodologies.

Basic Information

Product Name	tert-Butyl 2-Phenyl-6,7-dihydro-2H-pyrazolo[4,3-c]pyridine-5(4H)-carboxylate
CAS No.	1310796-20-3
Molecular Formula	C17H21N3O2
Molecular Weight	299.37 g/mol
Synonyms	tert-Butyl 2-phenyl-4,5,6,7-tetrahydro-2H-pyrazolo[4,3-c]pyridine-5-carboxylate; 2H-Pyrazolo[4,3-c]pyridine-5(4H)-carboxylic acid, 6,7-dihydro-2-phenyl-, 1,1-dimethylethyl ester; 5-Boc-2-phenyl-4,5,6,7-tetrahydro-2H-pyrazolo[4,3-c]pyridine; 2-Phenyl-5-(tert-butoxycarbonyl)-4,5,6,7-tetrahydro-2H-pyrazolo[4,3-c]pyridine; BOC-Protected 2-phenyl-6,7-dihydro-2H-pyrazolo[4,3-c]pyridin-5(4H)-one precursor
EINECS	Contact for details

Quality Control

Our tert-Butyl 2-Phenyl-6,7-dihydro-2H-pyrazolo[4,3-c]pyridine-5(4H)-carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specification results. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The compound may be hygroscopic; keep the container tightly sealed in a dry environment to prevent moisture uptake. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.