Description

5-Bromo-2-Fluoro-n-Methylnicotinamide is a high-purity, advanced pharmaceutical intermediate with a distinct halogenated pyridine structure. This compound is valued for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in kinase inhibitor research. It is primarily sought by R&D laboratories and production facilities in the pharmaceutical and agrochemical sectors for developing next-generation therapeutic and crop protection agents.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of targeted kinase inhibitors and other small molecule drugs.
• Agrochemical Research: Used in the development of new herbicides and fungicides due to its bioactive pyridine core.
• Chemical Synthesis: Serves as a versatile building block for introducing bromo and fluoro substituents into complex molecular architectures.
• Material Science: Potential use in the research and development of specialty chemicals and functional materials.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development.

Basic Information

Product Name	5-Bromo-2-Fluoro-n-Methylnicotinamide
CAS No.	1310416-54-6
Molecular Formula	C7H6BrFN2O
Molecular Weight	233.04 g/mol
Synonyms	5-Bromo-2-fluoro-N-methylnicotinamide; 5-Bromo-2-fluoro-N-methyl-3-pyridinecarboxamide; 3-Pyridinecarboxamide, 5-bromo-2-fluoro-N-methyl-; 5-Bromo-2-fluoro-3-(methylcarbamoyl)pyridine; N-Methyl-5-bromo-2-fluoronicotinamide
EINECS	Contact for details

Quality Control

Our 5-Bromo-2-Fluoro-n-Methylnicotinamide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with customer specifications and supporting regulatory filings for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). This material is moisture-sensitive (hygroscopic); keep the container tightly sealed under an inert atmosphere if necessary.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residual Solvents (GC)	Complies with ICH guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.